[Correspondence] Adequate SIRT activity dose is as important as adequate chemotherapy dose – Authors' reply

The FOXFIRE, SIRFLOX, and FOXFIRE-Global studies investigated the efficacy of combining first-line chemotherapy for metastatic colorectal cancer with selective internal radiotherapy (SIRT) using yttrium-90 resin microspheres in patients with liver metastases.1 The studies were designed for a prospective, combined analysis of overall survival, but also reported secondary endpoints including radiological response and liver-specific progression-free survival.

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