Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

Gene-expression profiling defined the activated B-cell–like (ABC) and germinal-center B-cell–like (GCB) subgroups of diffuse large B-cell lymphoma (DLBCL), leaving approximately 10 to 20% of cases "unclassified." This phenotypic distinction is associated with overall survival after standard therapy…

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