Τετάρτη 24 Αυγούστου 2022

Langerhans cell histiocytosis of the hard palate in an infant

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Publication date: Available online 24 August 2022

Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

Author(s): Takeshi Togawa, Akinari Sugauchi, Kaori Oya, Yusuke Yokota, Emiko Tanaka Isomura

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Different indications between fluoroquinolone and amoxicillin

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Prior exposure to azithromycin and azithromycin resistance among persons diagnosed with Neisseria gonorrhoeae infection at a Sexual Health Clinic 2012-2019

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Abstract
Background
There is conflicting evidence on whether prior azithromycin (AZM) exposure is associated with reduced susceptibility to AZM (AZMRS) among persons infected with Neisseria gonorrhoeae (NG).
Methods
The study population included Public Health-Seattle & King County Sexual Health Clinic (SHC) patients with culture-positive NG infection at ≥1 anatomic site whose isolates were tested for AZM s usceptibility 2012-2019. We used multivariate logistic regression to examine the association of time since last AZM prescription from the SHC in ≤12 months with subsequent diagnosis with AZMRS NG (minimum inhibitory concentration [MIC] ≥2.0 µg/ml) and used linear regression to assess the association between number of AZM prescriptions in ≤12 months and AZM MIC level, controlling for demographic, behavioral, and clinical characteristics.
Results
A total of 2,155 unique patients had 2,828 incident NG infections, 156 (6%) of which were caused by AZMRS NG. AZMRS NG was strongly associated with receipt of AZM from the SHC in the prior 29 days (adjusted odds ratio [aOR] 6.76, 95% CI 1.76-25.90), but not with receipt of AZM in the prior 30-365 days. Log AZM MIC level was not associated with the number of AZM prescriptions within ≤12 months (Adjusted correlation [aCor] 0.0004, 95% CI -0.04, 0.037), but was associated with number of prescrip tions with <30 days (adjusted coefficient [aCoef] 0.56, 95% CI 0.13-0.98)
Conclusion
Recent individual-level AZM treatment is associated with subsequent AZMRS gonococcal infections. The long half-life and persistence of subtherapeutic levels of AZM may result in selection of resistant NG strains in persons with recent AZM use.
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The role of anterior segmental osteotomies in orthognathic surgery for protrusive faces

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The objective of this study was to investigate the treatment outcomes of surgical versus orthodontic retraction in patients with bimaxillary protrusion undergoing orthognathic surgery. A retrospective cohort study was conducted, where the medical records and radiographs of 51 patients with bimaxillary protrusion who had an anterior segmental osteotomy concomitant with orthognathic surgery were examined. (Source: International Journal of Oral and Maxillofacial Surgery)
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Bone resorption after maxillary reconstruction with the vascularized free iliac flap

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The aim of this study was to evaluate the resorption of the iliac bone after maxillary reconstruction with a vascularized free iliac flap. Twenty-seven patients with maxillary defects who underwent maxillary reconstruction with the vascularized free iliac flap between January 2017 and January 2021 were included. Computed tomography (CT) images taken at 1 week, approximately 6 months, and 1 year after the surgery were used for evaluation. The total iliac bone thickness and height, cortical bone thickness, and cancellous bone density were measured in the CT images. (Source: International Journal of Oral and Maxillofacial Surgery)
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Do dental implants facilitate bone invasion in patients with oral squamous cell carcinoma? A case series

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Osseointegrated dental implants in the vicinity of oral squamous cell carcinoma (OSCC) will become more common given the increasing popularity of dental implants. Reports and studies of OSCC around dental implants are rare, as is the topic of how to handle OSCC surgically when implants are in contact with the tumour. In view of this uncertainty, a histological study was performed to assess tumour behaviour around implants. The aim was to determine whether an implant facilitates inward growth of the tumour and how this should be taken into account during staging and treatment planning. (Source: International Journal of Oral and Maxillofacial Surgery)
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Variability in the Estimated Amplitude of Vowel-Evoked Envelope Following Responses Caused by Assumed Neurophysiologic Processing Delays

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AbstractVowel-evoked envelope following responses (EFRs) reflect neural encoding of the fundamental frequency of voice (f0). Accurate analysis of EFRs elicited by natural vowels requires the use of methods like the Fourier analyzer (FA) to consider the production-relatedf0 changes. The FA 's accuracy in estimating EFRs is, however, dependent on the assumed neurophysiological processing delay needed to time-align thef0 time course and the recorded electroencephalogram (EEG). For male-spoken vowels (f0 ~ 100 Hz), a constant 10-ms delay correction is often assumed. Since processing delays vary with stimulus and physiological factors, we quantified (i) the delay-related variability that would occur in EFR estimation, and (ii) the influence of stimulus frequency, non-f0 related neural ac...
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