Πέμπτη 8 Δεκεμβρίου 2022

Association between masticatory dysfunction and gastroesophageal reflux disease: a population‐based study in the elderly

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Abstract

Background

Caries and periodontal disease may cause tooth losses and chewing difficulty, especially in the elderly. Ingesting poorly chewed food may delay gastric emptying and favor the development of gastroesophageal reflux disease (GERD).

Objective

This study investigated the association between masticatory dysfunction and GERD in the elderly from a rural area in southern Brazil.

Methods

This census invited all 489 elderly from a city to participate. The study used a GERD symptoms questionnaire, followed by an oral examination. Masticatory dysfunction was analyzed based on the chewing difficulty for some food groups. Tooth loss and chewing self-perception were also considered as exposure variables. Poisson regression determined the association among variables by calculating the prevalence ratio [PR(95% confidence interval)].

Results

The response rate was 93.1% (n=455, average age of 70.9 years, 50.5% men). The prevalence of GERD in this population was 36.9%. GERD was associated with chewing difficulty for vegetables (PR=1.54), meats (PR=1.34), and cereals (PR=1.43) but not with poor chewing self-perception (PR=0.80) and tooth loss (PR=1.22). GERD was also associated with xerostomia (PR=1.63) and the female gender (PR=1.35).

Conclusions

Elderly people from a rural area with a reduced number of teeth present chewing difficulty and a high prevalence of GERD, indicating an association between GERD and masticatory dysfunction.

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Mapping schistosomiasis risk in Southeast Asia: a systematic review and geospatial analysis

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Abstract
Background
Schistosomiasis is a water-borne parasitic disease estimated to have infected >140 million people globally in 2019, mostly in sub-Saharan Africa. Within the goal of eliminating schistosomiasis as a public health problem by 2030 in the World Health Organization (WHO) Roadmap for neglected tropical diseases, other regions cannot be neglected. Empirical estimates of the disease burden in Southeast Asia largely remain unavailable.
Methods
We undertook a systematic review to identify empirical survey data on schistosomiasis prevalence in Southeast Asia using the Web of Science, ScienceDirect, PubMed and the Global Atlas of Helminth Infections, from inception to 5 February 2021. We then conducted advanced Bayesian geostatistical analysis to assess the geographical distribution of infection risk at a high spatial resolution (5 × 5 km) using the prevalence, number of infected individuals and doses needed for preventi ve chemotherapy.
Results
We identified 494 Schistosoma japonicum surveys in the Philippines and Indonesia, and 285 in Cambodia and Laos for S. mekongi. The latest estimates suggest that 225 [95% credible interval (CrI): 168–285] thousand in the endemic areas of Southeast Asian population were infected in 2018. The highest prevalence of schistosomiasis was 3.86% (95% CrI: 3.40–4.31) in Laos whereas the lowest was 0.29% in Cambodia (95% CrI: 0.22–0.36). The estimated number of praziquantel doses needed per year was 1.99 million (95% CrI: 1.92–2.03 million) for the entire population in endemic areas of Southeast Asia.
Conclusions
The burden of schistosomiasis remains far from the WHO goal and our estimates highlighted areas to target with strengthened interventions against schistosomiasis.
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Optimizing the Assessment of Olfactory Dysfunction

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In this issue of JAMA Otolaryngology–Head & Neck Surgery, Lee et al report their development and validation of a novel patient-reported outcome measure (PROM) of smell loss–related quality of life, the 28-item Olfactory Dysfunction Outcomes Rating (ODOR). ODOR represents a visually appealing, straightforward, concise, and patient-centered instrument to assess the physical problems, functional limitations, and emotional consequences of olfactory dysfunction.
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Tonsillectomy vs Modified Uvulopalatopharyngoplasty for Hypertrophy and Obstructive Sleep Apnea

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This randomized clinical trial examines whether modified uvulopalatopharyngoplasty is more effective than tonsillectomy alone for treating adults with tonsillar hypertrophy and moderate to severe obstructive sleep apnea.
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Development of the Taste And Smell Tool for Evaluation

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This survey study develops and validates an instrument wit h all relevant domains concerning chemosensory dysfunction and quality of life using modern psychometrics.
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American Thyroid Association Guidelines and Management of Papillary Thyroid Carcinoma

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This cohort study determines how the 2009 and 2015 Americ an Thyroid Association guidelines may have corresponded with trends in the management of patients with low-risk papillary thyroid carcinoma.
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Berichtetes und gemessenes Riech- und Schmeckvermögen in einer Long-COVID-Kohorte

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Laryngorhinootologie
DOI: 10.1055/a-1970-6510

Einleitung Störungen des Riech- und Schmecksinns werden häufig zahlenmäßig übereinstimmend als Long-COVID-Symptom beklagt. Anhand von Befunden einer Spezialsprechstunde (HNO-LCS) soll geklärt werden, wie groß tatsächlich der Anteil pathologischer olfaktorischer bzw. gustatorischer Diagnosen in dieser Kohorte ist. Methodik 48 erwachsene Patienten, die die HNO-LCS aus eigenem Leidensdruck aufsuchten, wurden nach ihrer Anamnese befragt, sie schätzten ihr Riech- (SER) und Schmeckvermögen (SES) mit Schulnoten ein und absolvierten als Riechtest den erweiterten Sniffin'Sticks-Test und als Schmecktest den 3-Tropfen-Test. Aus dem SDI-Riechscore und dem totalen Schmeckscore (SScore-total) wurden anhand von Normwerten Diagnosen erstellt. Zwischen den gemessenen Scores und der Selbsteinschätzung und zwischen SER und SES wurden Korrelationen berechnet. Ergebnisse Tatsächliche pathologische chemosensorische Diagnosen bestanden bei 90% der Patienten. Pathologische olfaktorische Diagnosen waren doppelt so häufig wie gustatorische. Bei 10% der Kohorte war keine pathologische Diagnose verifizierbar. Bei 6 Patienten wurde ein Anosmie-Ageusie-Syndrom diagnostiziert. SER korrelierte stark mit SDI. SES korrelierte moderat mit SScore-total. SER korrelierte stark mit SES. Schlussfolgerungen Bei der Interpretation berichteter chemosensorischer Symptome besteht die Gefahr einer Konfusion von Riechen und Schmecken durch die Betroffenen. Deshalb ist die Überprüfung der chemischen Sinne mit validierten Tests in Long-COVID-Ambulanzen wichtig.
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Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

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