An experimental strategy for treating advanced ovarian cancer has caused tumor regression in animal models, according to a new study. The strategy uses a protein fragment, or peptide, to stimulate normal cells in the tissues surrounding cancer cells—the tumor microenvironment—to block the growth of the cancer cells.
Suming Wang, Ph.D., and Anna Blois, Ph.D., of Boston Children's Hospital's Vascular Biology Program and their colleagues, reported the results March 9 in Science Translational Medicine. Based on the findings, the researchers said they would continue to explore this strategy as a potential treatment for ovarian cancer that has spread to other parts of the body, or metastasized.
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