I-SPY 2 — A Glimpse of the Future of Phase 2 Drug Development?

The articles by Rugo et al. (pages 23–33) and Park et al. (pages 11–22) in this issue of the Journal report results from the I-SPY (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging and Molecular Analysis) 2 platform, a promising adaptive strategy for matching…

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