Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

Carcinoma of the prostate is a common cancer with a wide spectrum of clinical behavior that ranges from decades of indolence to rapid metastatic progression and lethality. Prostate cancer is also among the most heritable of human cancers, with 57% (95% confidence interval [CI], 51 to 63) of the…

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