Παρασκευή 4 Αυγούστου 2017

Randomized Controlled Trials in Soft Tissue Sarcoma: We Are Getting There!

Publication date: Available online 4 August 2017
Source:Surgical Oncology Clinics of North America
Author(s): Andrea J. MacNeill, Abha Gupta, Carol J. Swallow

Teaser

Soft tissue sarcoma (STS) is a family of malignancies for which individual management decisions can be complex. There is a paucity of level 1 evidence, as the rarity and heterogeneity of STS pose challenges to the design and execution of randomized controlled trials. Radiotherapy (RT) is routinely used to facilitate function-preserving surgery and to improve local control. Delivery of RT in the preoperative setting can decrease chronic toxicities at the cost of increased wound complications in the short-term. The role of adjuvant systemic therapies remains controversial in adult STS.


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