Epidermal growth factor as a potential prognostic and predictive biomarker of response to platinum-based chemotherapy

xlomafota13 shared this article with you from Inoreader Epidermal growth factor as a potential prognostic and predictive biomarker of response to platinum-based chemotherapy Via Head and neck cancers by Margot Geens, Sofie Stappers, Heleen Konings, Benedicte Y. De Winter, Pol Specenier, Jan P. Van Meerbeeck, Gert A. Verpooten, Steven Abrams, Annelies Janssens, Marc Peeters, Paul Van de Heyning, Olivier M. Vanderveken, Kristien J. Ledeganck In this study, we investigated serum epidermal growth factor (EGF) in an oncological population of head- and neck and pulmonary neoplasms and whether serum EGF could serve as a prognostic marker of survival and as a predictive marker for treatment response to platinum-based chemotherapy. A total of 59 oncological patients and a control group of age- and sex-matched healthy volunteers were included in this study. Pre-treatment serum EGF from both groups was determined. Patient's and tumour characteristics and mortality were recorded during a 5-year follow up period. Baseline serum EGF significantly differed between the oncological patients and the healthy volunteers (p View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.