Cholesterol: An Achilles’ Heel for Glioblastoma?

Publication date: 14 November 2016
Source:Cancer Cell, Volume 30, Issue 5
Author(s): Zhenyi An, William A. Weiss
In this issue of Cancer Cell, Villa et al. report that survival of glioblastoma cells is dependent on uptake of cholesterol. A synthetic agonist of the Liver X receptor depleted cholesterol in GBM cells, slowing growth of GBM xenografts.

Teaser

In this issue of Cancer Cell, Villa et al. report that survival of glioblastoma cells is dependent on uptake of cholesterol. A synthetic agonist of the Liver X receptor depleted cholesterol in GBM cells, slowing growth of GBM xenografts.


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