Τετάρτη 30 Νοεμβρίου 2016

hERG channels: from antitargets to novel targets for cancer therapy

In this issue of Clinical Cancer Research, evidence is provided on how to avoid cardiotoxicity when targeting hERG K+ channel for cancer therapy. hERG regulates different aspects of neoplastic progression. Although its blockade has effective anticancer effects in experimental models, it may lead to fatal arrhythmias in humans. Conclusions:



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