Δευτέρα 26 Μαρτίου 2018

The long neglected player: modeling tumor uptake to guide optimal dosing

Pharmacokinetic modeling is widely used to support decision making in translational medicine and patient care, traditionally using circulating drug exposure. The development of mechanistic computational models that integrate drug concentrations at the site of action making use of existing knowledge opens a new paradigm in optimal dosing.



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