Mohammad Moin Shahid, Khadiza Begum, Kaniz Rahman, Hosnea Ara, Sharmin Ferdousi, Richmond Ronald GomesThyroid Research and Practice 2021 18(1):19-22
Background and Objectives: Due to geographical position and geological nature, Bangladesh (BD) has been the worst affected country in the world by arsenic contamination. The aim of this study was to highlight the association of chronic arsenic intoxication with thyroid disorders (TDs). Materials and Methods: This cross-sectional study was conducted from March 2019 to February 2020 at Ad-din Women's Medical College and Hospital. One thousand one hundred and thirty-seven patients were randomly selected, who visited the outpatient departments of medicine faculty with thyroid-stimulating hormone test report. Rest of the thyroid function tests were done if required. Considering the arsenic level in irrigation and drinking water, 64 districts of BD were divided into two regions "arsenic prevalent area" and "less arsenic prevalent area" and patients hailing from those areas were divided as Group 1 and Group 2, respectively. All patients were subjected to history taking and physical examination. Chi-square test and one-way ANOVA test were used to compare the variables. Results: Prevalence of TD were significantly higher in Group 1 (60.14%; P = 0.001) and so was the prevalence of goiter (19%;P = 0.021). Older (31.17 ± 9.81;P = 0.001) and female patients (94.92%;P = 0.001) were more prone to develop TD. Conclusion: It will require more studies at larger scale for better understanding of the association of thyroid disorders with chronic arsenic intoxication.
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