Current Management of Newly Diagnosed Acute Promyelocytic Leukemia

Appropriate diagnosis and management of Acute Promyelocytic Leukemia is of utmost importance to reduce the risk of early mortality. The standard front-line approach with ATRA and chemotherapy has been recently challenged by ATRA and ATO combination, which has emerged as the new standard of care for non-high risk disease. In light of the recent progress, several therapeutic and monitoring issues are currently matter of debate in the novel therapeutic contexts.

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