Interfering with CCL5/CCR5 at the Tumor-Stroma Interface

Publication date: 11 April 2016
Source:Cancer Cell, Volume 29, Issue 4
Author(s): Vincenzo Bronte, Emilio Bria
In this issue of Cancer Cell, Halama et al. (2016) further advance chemokine interference as a therapeutic option for cancer by demonstrating the effect of CCR5 blockade in reshaping macrophage polarization toward an anti-tumor functional state in patient-derived tumor models and liver metastases of colorectal cancer patients.

Teaser

In this issue of Cancer Cell, Halama et al. (2016) further advance chemokine interference as a therapeutic option for cancer by demonstrating the effect of CCR5 blockade in reshaping macrophage polarization toward an anti-tumor functional state in patient-derived tumor models and liver metastases of colorectal cancer patients.


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