Glycoholics Anonymous: Cancer Sobers Up with mTORC1

Publication date: 11 April 2016
Source:Cancer Cell, Volume 29, Issue 4
Author(s): Vivian Fu, Toshiro Moroishi, Kun-Liang Guan
In this issue of Cancer Cell, Pusapati et al. (2016) reveal that mTORC1 orchestrates the metabolic reprogramming of cancer cells in response to glycolytic inhibitors, bypassing glycolysis by increasing glutamine uptake and pentose phosphate flux to generate energy and biomass.

Teaser

In this issue of Cancer Cell, Pusapati et al. (2016) reveal that mTORC1 orchestrates the metabolic reprogramming of cancer cells in response to glycolytic inhibitors, bypassing glycolysis by increasing glutamine uptake and pentose phosphate flux to generate energy and biomass.


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