Human Cancer Models Initiative Will Create Next Generation Cancer Models That Have Genomic and Clinical Data

Experimental studies using cancer cell lines are an essential step in successful cancer research. Researchers use cell lines to discover new genes involved in cancer, test the biological function of genes, and even develop and evaluate new treatments. 

However, most cancer cell lines in use today do not provide scientists with a complete toolkit for their research. They lack the architecture and complexity of human tissue, as well as key information that can inform research, such as genomic and clinical profiles. Moreover, given the great genetic diversity of cancer, many common and rare subtypes of cancer are inadequately represented among existing cancer cell lines. That's why the NCI has joined forces with the foremost experts in novel cell culture techniques to generate new models of cancer that more accurately represent human tumors.

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