Πέμπτη 8 Δεκεμβρίου 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

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Adoptive cell therapy using ex vivo expanded tumor-infiltrating lymphocytes has led to durable complete regression of tumors in 20 to 25% of patients with metastatic melanoma. This effect is probably mediated by T cells that specifically target mutant peptides encoded by de novo somatic mutations,…

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