[Perspectives] Antineoplastons: when is enough enough?

Antineoplastons are an experimental cancer therapy that is not approved by the US Food and Drug Administration (FDA) for any indication. To date, there have been no randomised, controlled trials showing efficacy of antineoplastons. However, side-effects of this therapy can include serious neurological toxicity. So, how can such therapy continue to be in use after more than four decades, and be administered to thousands of patients, without any proven safety or activity data?

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