Πέμπτη 10 Μαρτίου 2022

Hearing preservation in cochlear implant recipients: A cross‐sectional cohort study

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Abstract

Objectives

A surge of new developments and research regarding cochlear implants and hearing preservation resulted in several treatment options in the last 5 years. By reviewing our CI population of this period, we aimed to investigate hearing preservation rates and the effect of different treatment options on hearing preservation.

Design

Retrospectively, all adult cochlear implant recipients with preoperative residual hearing at lower frequencies (threshold <80 dB hearing level) in a single tertiary referral centre between 2015 and 2020 were analysed. Patients were classified into four groups based on their hearing preservation outcome. Subsequently, differences between the four groups regarding several patient dependent and independent factors were investigated.

Results

In this study, 140 patients were included, which is 46% of all adult CI recipients. Complete hearing preservation was achieved in 14 patients (10%), and complete loss of residual hearing in 48 patients (34%). The lateral wall array and local application of corticosteroids were associated with better hearing preservation. Intravenous corticosteroids, local hyaluronic acid and surgical experience had no effect on hearing preservation rates. Speech perception was not better in patients with residual hearing.

Conclusion

Approximately half of all adult cochlear implant recipients had residual hearing at lower frequencies before surgery. In current medical practice, only electrode choice seems to have a clear effect on hearing preservation rates. The majority of CI recipients lose their residual hearing after cochlear implantation. Much improvement in treating CI recipients is needed to preserve their residual hearing in the future.

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Porokeratosis: a differential diagnosis to consider in benign lichenoid keratosis

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Int J Clin Exp Pathol. 2022 Feb 15;15(2):56-62. eCollection 2022.

ABSTRACT

Porokeratosis is a disorder of keratinization with many clinical variants. The histological hallmark feature of porokeratosis is a cornoid lamella. Other accompanying features include lichenoid inflammation, atrophy towards the centre of the lesion, dermal cytoid bodies, and adjacent lichenoid changes. Lichenoid keratosis is a benign cutaneous condition, thought to largely represent a degenerating seborrheic keratosis or solar lentigo. The classical histologic appearances are characterized by parakeratosis, epidermal acanthosis, and a dense band of lichenoid lymphocytic infiltrate. Since a lichenoid inflammatory reaction pattern can be seen in porokeratosis it has the potential to be misdiagnosed as a lichenoid keratosis if the cornoid lamella is not identified or missed due to sampling selection. We critically review 104 cases of benign lichenoid keratosis to e stablish whether any of these cases had features to support a diagnosis of porokeratosis. With 9.6% of cases considered for re-classification, we review clues to reaching this histologic diagnosis.

PMID:35265253 | PMC:PMC8902476

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Epidemiology and Management of Zenker Diverticulum in a Low-Threshold Single-payer Health Care System

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This cohort study examines population-wide incidence of Z enker diverticulum in Finland over a 20-year period and management strategies across specialties and treatment settings.
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Quality Indicators for the Diagnosis and Management of Primary Hyperparathyroidism

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This quality improvement study develops quality indicator s to evaluate the diagnosis and treatment of primary hyperparathyroidism that could measure, improve, and optimize quality of care and outcomes for patients with this disease.
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Use of FDG-PET/CT to Predict Immunotherapy Treatment Response in Patients With OCSCC

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This study assesses whether there are changes on fluoro-[ 18F]-deoxy-2-D-glucose positron emission tomography/computed tomography scans in patients with oral cavity squamous cell cancer receiving neoadjuvant immunotherapy.
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Development and Validation of a Novel At-home Smell Assessment

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This diagnostic study develops and validates a simple scr eening assessment for olfactory dysfunction using common household items.
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Is a 4-Day Low-Iodine Diet Sufficient for Radioactive Iodine Ablation in Differentiated Thyroid Cancer Treatment?

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Clinical Thyroidology, Volume 34, Issue 3, Page 123-126, March 2022.
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Prevalence of “Higher-Risk” Adverse Histological Features Found at Autopsy in Patients with Occult Differentiated Thyroid Cancer

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Clinical Thyroidology, Volume 34, Issue 3, Page 127-131, March 2022.
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The Role of a Computer-Aided Diagnosis System in the Interpretation of Thyroid Nodules with Challenging Sonographic Features

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Clinical Thyroidology, Volume 34, Issue 3, Page 112-115, March 2022.
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Pharyngolaryngeal Morbidity With the Laryngeal Mask Airway SupremeTM at Different Fiberoptic Bronchoscopy Grades: An Observational Study

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To assess whether the different fiberoptic bronchoscopy (FOB) grades of laryngeal mask airway (LMA) Supreme™ affects pharyngolaryngeal morbidity (PLM, including sore throat, dysphonia, pharyngoxerosis, and dysphagia) after general anesthesia.
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Surgical Outcomes Following Vestibular Schwannoma Resection in Patients over the Age of Sixty-five

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J Neurol Surg B Skull Base
DOI: 10.1055/a-1771-0504

Objective Vestibular schwannoma (VS) are benign, often slow growing neoplasms. Some institutions opt for radiosurgery in symptomatic patients of advanced age versus surgical resection. The aim of the study is to analyze surgical outcomes of VS in patients over the age of 65 who were either not candidates for or refused radiosurgery. Methods This includes retrospective analysis of VS patients between 1988 and 2020. Demographics, tumor characteristics, surgical records, and clinical outcomes were recorded. Patient preference for surgery over radiosurgery was recorded in the event that patients were offered both. Facial nerve outcomes were quantified using House-Brackmann (HB) scores. Tumor growth was defined by increase in size of >2 mm. Results In total, 64 patients were included of average age 72.4 years (65–84 years). Average maximum tumor diameter was 29 mm (13–55 mm). Forty-five patients were offered surgery or GKRS, and chose surgery commonly due to radiation aversion (48.4%). Gross total resection was achieved in 39.1% (n = 25), near total 32.8% (n = 21), and subtotal 28.1% (n = 18). Average hospitalization was 5 days [2–17] with 75% (n = 48) discharged home. Postoperative HB scores were good (HB1–2) in 43.8%, moderate (HB3–4) in 32.8%, and poor (HB5–6) in 23.4%. HB scores improved to good in 51.6%, moderate in 31.3%, and remained poor in 17.1%, marking a rate of facial nerve improvement of 10.9%. Tumor control was achieved in 95.3% of cases at an average follow-up time of 37.8 months. Conclusion VS resection can be safely performed in patients over the age of 65. Advanced age should not preclude a symptomatic VS patient from being considered for surgical resection.
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Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

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Minipterional Approach for Middle Fossa Skull Base Lesions: Technical Note

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J Neurol Surg B Skull Base
DOI: 10.1055/s-0042-1743464

Surgical access to the middle fossa can be technically challenging. As neurosurgery evolves to minimally invasive approaches, the objective of this study is to demonstrate the extension of the Minipterional approach to access the middle fossa. We present a new surgical approach to the middle fossa for the treatment of secondary trigeminal neuralgia. Three cases are reported to illustrate the following techniques: a patient with petrotentorial meningioma and trigeminal neuralgia, a patient with an arachnoid cyst compressing the fifth nerve, and a patient with a middle cerebral artery aneurysm and a long history of TN (trigeminal neuralgia) refractory to medical and surgica l treatments. All three experienced full symptom controls with no permanent neurological deficits. Therefore, the Minipterional technique might represent a feasible, effective, and safe option to treat refractory secondary TN. It also allows approaching these lesions when the posterior fossa approach is compromised by anatomical distortion and enables the simultaneous treatment of secondary trigeminal neuralgia and other lesions, such as aneurysms and meningiomas.
[...]

Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

Article in Thieme eJournals:
Table of contents  |  Abstract  |  Full text

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