Endoscopic surgery for intraconal orbital tumors

xlomafota13 shared this article with you from Inoreader Endoscopic surgery for intraconal orbital tumors Via hno HNO. 2022 Mar 17. doi: 10.1007/s00106-022-01156-y. Online ahead of print. ABSTRACT Traditionally, external craniofacial approaches have been used for orbital tumor resection. Over the last 30 years, endoscopic sinonasal and skull base techniques have become widely used throughout the world. These experiences paved the way for the extension of transnasal endoscopic techniques to the intraconal orbit. Transnasal endoscopic intraconal surgery has several advantages regarding mo rbidity and outcome as compared with purely external approaches. However, the anatomical knowledge and experience of the surgeon is crucial for the success of the surgery. Endoscopic approaches for intraconal tumor removal are feasible for medial and inferior lesions as well as for lesions lateral to the optic nerve provided they remain inferior to the "plane of resectability" and no optic nerve retraction is required. As intraorbital tumors are rare, new international staging systems including CHEER (Cavernous Hemangioma Exclusively Endonasal Resection) and ORBIT (Orbital Resection by Intranasal Technique) help to standardize safety, efficacy, and outcome. PMID:35298667 | DOI:10.1007/s00106-022-01156-y View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Evaluation of thermal plasma process for treatment disposal of solid radioactive waste

xlomafota13 shared this article with you from Inoreader Evaluation of thermal plasma process for treatment disposal of solid radioactive waste Via radioactive iodine J Environ Manage. 2022 Mar 14;311:114895. doi: 10.1016/j.jenvman.2022.114895. Online ahead of print. ABSTRACT The management of radioactive waste is a worldwide activity based on the guidelines of the International Atomic Energy Agency (IAEA), and all stages of management require scientifically proven methods for possible deployment. The management of radioactive waste is a huge challenge due to the high risk in the collection, gathering, transport, handling, and storage. In this s tudy, a thermal plasma treatment process was evaluated for its efficiency to process solid radioactive waste. Experiments were carried out with the application of stable isotopes of Lead, Iodine, Cobalt, and Cesium. After the thermal plasma treatments, the slag and the residual gas were analyzed to verify the influence of process time and discharge power on the efficiency of the process. The treatment for 25 min and 10 kW was sufficient to reduce the mass by 50% of the slag. When the applied power was increased to 15 kW, an expressive reduction in the treatment time (10 min) was able to promote the same mass reduction. The results indicated that the treatment of radioactive waste by thermal plasma is a promising method to manage and reduce the mass and volume for the final disposal. PMID:35299134 | DOI:10.1016/j.jenvman.2022.114895 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Anatomic evaluation of the triceps tendon insertion at the proximal olecranon regarding placement of fracture fixation devices

xlomafota13 shared this article with you from Inoreader Anatomic evaluation of the triceps tendon insertion at the proximal olecranon regarding placement of fracture fixation devices Via radiol anat Surg Radiol Anat. 2022 Mar 17. doi: 10.1007/s00276-022-02921-y. Online ahead of print. ABSTRACT PURPOSE: Olecranon fractures, especially with a small proximal fragment, remain a surgical challenge. Soft tissue irritation and affection of the triceps muscle bear a risk of complications. In order to find an area for a soft-tissue sparing placement of implants in the treatment of olecranon fractures, we aimed to define and measure the segments of the proximal olecranon and eval uate them regarding possible plate placement. METHODS: We investigated 82 elbow joints. Ethical approval was obtained from the local ethics committee, After positioning in an arm holder and a posterior approach we described the morphology of the triceps footprint, evaluated and measured the surface area of the triceps and posterior capsule and correlated the results to easily measurable anatomical landmarks. RESULTS: We found a bipartite insertional footprint with a superficial tendinous triceps insertion of 218.2 mm2 (± 41.2, range 124.7-343.2), a capsular insertion of 159.3 mm2 (± 30.2, range 99.0-232.1) and a deep, muscular triceps insertion area of 138.1 mm2 (± 30.2, range 79.9-227.5). Olecranon height was 26.7 mm (± 2.3, range 20.5-32.2), and olecranon width was 25.3 mm (± 2.4, range 20.9-30.4). Average correlation between the size of the deep insertion and ulnar (r = 0.314) and radial length (r = 0.298) was obtained. CONC LUSIONS: We demonstrated the bipartite morphology of the distal triceps footprint and that the deep muscular triceps insertion area by its measured size could be a possible site for the placement of fracture fixations devices. The size correlates with ulnar and radial length. PMID:35301578 | DOI:10.1007/s00276-022-02921-y View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Radiological score of computed tomography scans predicts revision surgery for chronic rhinosinusitis

xlomafota13 shared this article with you from Inoreader Radiological score of computed tomography scans predicts revision surgery for chronic rhinosinusitis Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2022 Feb;42(1):63-74. doi: 10.14639/0392-100X-N1561. ABSTRACT OBJECTIVE: Evaluate computed tomography (CT) signs that predict need for revision endoscopic sinus surgery (ESS) of chronic rhinosinusitis (CRS). METHODS: CRS patients (n = 48) underwent routine sinus CT scans and baseline ESS in 2006-2011. Lund-Mackay (LM) scores and 43 other CT signs were analysed blinded from both sides. Patients filled in a questionnaire during the day of CT s canning. Follow-up data were collected from hospital records until January 2018. Associations were analysed by Fisher's exact, Mann Whitney U, Kaplan-Meier method with logrank test and Cox's proportional hazard model. RESULTS: Total LM score was not significantly associated with the need for revision ESS. The best predictive model was a sum of CT signs of non-detectable anatomy of inferior/middle turbinates, obstructed frontal recess, and previous sinus surgery. Using these CT findings, we formed a Radiological Score (RS) (min-max, 0-3 points). Having at least one RS point was significantly associated with the need for revision ESS during the average follow-up of 10.7 years (p = 0.008, Logrank test). CONCLUSION: We identified a radiologic score that was able to predict the need for revision ESS, which is probably useful in predicting CRS outcomes. PMID:35292788 | DOI:10.14639/0392-100X-N1561 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Relationship of PPARG overexpression with prognostic parameters in papillary thyroid carcinoma

xlomafota13 shared this article with you from Inoreader Relationship of <em>PPARG</em> overexpression with prognostic parameters in papillary thyroid carcinoma Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2022 Feb;42(1):34-40. doi: 10.14639/0392-100X-N1034. ABSTRACT OBJECTIVES: PAX8/PPARG chromosomal rearrangement is frequently seen in thyroid cancer, and PPARG overexpression has been shown in the follicular variant of papillary thyroid carcinoma, but not in papillary thyroid carcinoma other than the follicular variant. The main aim of this study was to investigate the frequency of PPARG overexpression among papillary thyroid ca rcinoma and if there were any variants of papillary thyroid carcinoma with PPARG overexpression other than the follicular variant. METHODS: Immunohistochemical analysis of PPARG overexpression was performed using a PPARG monoclonal antibody in a series of 111 paraffin-embedded blocks of thyroid tumours. Of the patients in our study, 100 were diagnosed with papillary thyroid carcinoma, 9 with follicular adenoma and 2 with follicular carcinoma. RESULTS: PPARG staining was detected in 19 of the 111 cases. Sixteen patients with PPARG overexpression had papillary thyroid carcinoma and 3 had follicular adenoma. CONCLUSION: PPARG overexpression was detected mainly in follicular-variant papillary thyroid carcinoma. Vascular invasion, lymphatic invasion, thyroid capsule invasion and lymph node positivity were lower in patients with PPARG overexpression. PMID:35292786 | DOI:10.14639/0392-100X-N1034 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Association Between Anxiety and Descending Pain Modulation of Thermal Stimuli in Patients with Burning Mouth Syndrome: A Cross-Sectional Study

xlomafota13 shared this article with you from Inoreader Association Between Anxiety and Descending Pain Modulation of Thermal Stimuli in Patients with Burning Mouth Syndrome: A Cross-Sectional Study Via pubmed: "j oral facial pain ... J Oral Facial Pain Headache. 2022 Winter;36(1):67-77. doi: 10.11607/ofph.3050. ABSTRACT AIMS: To investigate the predictive power of depression and anxiety for conditioned pain modulation (CPM) and to examine the relationships of CPM at 40°C and CPM at 47°C with age, disease-related pain, pain duration, and psychosocial factors in burning mouth syndrome (BMS). METHODS: A total of 22 patients with BMS and 22 healthy female controls participated in this study. Temporal summation was used as the test stimulus for CPM, and subsequent exposure either to a nonpainful (40°C) or a painful (47°C) Peltier thermode was used as the conditioning stimulus. CPM was calculated as the difference in pain perception following the conditioning stimulus. Psychosocial factors were examined using the Profile of Mood States (POMS) and the State-Trait Anxiety Inventory (STAI). RESULTS: State anxiety and tension-anxiety scores were significantly higher for patients with BMS than for control participants. Multiple regression analyses showed that CPM47°C was affected by vigor, fatigue, confusion, and trait anxiety (adjusted R2 = 0.685, F = 5.147, P = .098). The corresponding analysis for CPM40°C showed that the model was not predictive for the following variables: disease-related pain, pain duration, or components of the POMS or STAI. A significant positive correlation was found between CPM47°C and trait anxiety, suggesting that trait anxiety negativ ely affected the endogenous pain modulation system. CONCLUSION: Increases in trait anxiety reduced the CPM effect. These findings suggest that CPM impairments and increases in trait anxiety are involved in the development of BMS. PMID:35298577 | DOI:10.11607/ofph.3050 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

A Narrative Review of Therapeutic Peripheral Nerve Blocks for Chronic Orofacial Pain Conditions

xlomafota13 shared this article with you from Inoreader A Narrative Review of Therapeutic Peripheral Nerve Blocks for Chronic Orofacial Pain Conditions Via pubmed: "j oral facial pain ... J Oral Facial Pain Headache. 2022 Winter;36(1):49-58. doi: 10.11607/ofph.3017. ABSTRACT AIMS: To provide an analysis of the different therapeutic peripheral nerve blocks (PNBs), as well as their limitations and the related evidence base for their use in chronic orofacial pain (OFP) conditions, excluding migraine and other headache conditions. METHODS/RESULTS: The evidence base for therapeutic PNBs for chronic OFP is poor and highlights the need for improved research in this area. The diagnostic criteria and interventional PNB definitions and techniques varied between studies. In addition, the placebo effect of a peripheral injection and its resultant bias was rarely considered. Most of the PNB interventions for temporomandibular disorders were for arthrogenous disorders (arthritis and disc entrapment with pain). However, there is emerging evidence for the use of onabotulinum toxin (BTX-A) in trigeminal neuralgia, with four prospective randomized controlled trials (pRCTs), and for postherpetic neuralgia. However, despite high-level evidence for BTX-A in posttraumatic neuropathic pain outside the trigeminal system, there is no evidence for its use for PTNP within the trigeminal system. CONCLUSION: There may be emerging evidence for treating trigeminal neuralgia with BTX-A injections; however, there is a need for future clinical studies of therapeutic PNBs in orofacial pain conditions. PMID:35298575 | DOI:10.11607/ofph.3017 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Oral exercises significantly improve oral functions in people with mild and moderate dementia: a randomized controlled study

xlomafota13 shared this article with you from Inoreader Oral exercises significantly improve oral functions in people with mild and moderate dementia: a randomized controlled study Via swallowing exercises J Oral Rehabil. 2022 Mar 11. doi: 10.1111/joor.13317. Online ahead of print. ABSTRACT BACKGROUND: There have been no standard protocols of oral exercises for maintaining and improving oral function for people with dementia. OBJECTIVE: This study aimed to determine the effects of home-based oral exercises on the oral function of people with mild to moderate dementia. METHODS: Twenty-two participants at King Chulalongkorn Memorial Hospital were randomly assigned to exercis e group (n = 11) or control group (n = 11). The exercise group was instructed to do three home-based oral exercises, consisting of tongue-strengthening, oral diadochokinesis (ODK), and mouth-opening exercises, for 3 months, while the control group received advice on oral health care. The maximum tongue pressure (MTP) was the primary outcome. MTP, ODK rates of /pa/, /ta/, /ka/, modified water swallowing test (MWST), and oral moisture were measured at baseline, and after 1, 2, and 3 months of training. The generalized estimating equation analysis was used to evaluate the effects of oral exercises on the oral function. RESULTS: The MTP and all ODK rates in the exercise group were significantly increased after 3 months of training. There were significant interaction effects between time and intervention in MTP and all ODK rates. No significant interaction effects between time and intervention in oral moisture were found. The MWST scores in both groups did not change through the en d of study and no adverse effects were reported. CONCLUSION: Home-based oral exercises were found to be effective for improving tongue strength and tongue-lip motor function in people with mild to moderate dementia. PMID:35274344 | DOI:10.1111/joor.13317 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Experimental model of unpredictable maternal stress and diabetes risk of offspring: An immunohistochemical study

xlomafota13 shared this article with you from Inoreader Experimental model of unpredictable maternal stress and diabetes risk of offspring: An immunohistochemical study Via histochem Acta Histochem. 2022 Mar 15;124(3):151878. doi: 10.1016/j.acthis.2022.151878. Online ahead of print. ABSTRACT The effect of stress on the occurrence of diabetes mellitus (DM) is commonly reported in recent studies. Maternal stress may have a negative effect on the later life of offspring. However, most studies only investigated long-term intrauterine stress on behavioral, emotional, psychological, and immunological disorders of offspring. The relationship between maternal st ress and DM occurrence in the later life period of offspring is not known. This rat model study aimed to evaluate the susceptibility of offspring to DM after exposure to intrauterine stress. The purpose of this study is to examine serum glucose levels of mothers and offspring exposed to maternal stress and to evaluate pancreatic tissues pathologically and immunohistochemically. Twelve, Wistar Albino female rats were equally divided into two groups: controls and maternal stress groups. Normal routine conditions were applied to the control group without any stress. The pregnant rats in the maternal stress group were exposed to chronic unpredictable stressors throughout the 21-day gestation. One female and one male offspring and mothers from each term delivery were randomly selected and euthanatized at the 35th day. During the necropsy, blood and pancreatic tissue samples were collected from both mothers and pups. High serum glucose levels from mothers and offspring in the maternal str ess group and the control group were compared. Additionally, histopathological examinations assessed the increased cell degeneration in mother rats and offspring. Immunohistochemical examinations revealed decreased insulin, amylin, and insulin receptor expressions and slightly increased glucagon expression in Langerhans islet cells in the maternal stress group. These results indicated that maternal stress may be a predisposing factor for DM in both mothers and offspring in their later life periods. PMID:35303510 | DOI:10.1016/j.acthis.2022.151878 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Rodlet cells in kidney of goldfish (Carassius auratus, Linnaeus 1758): A light and confocal microscopy study

xlomafota13 shared this article with you from Inoreader Rodlet cells in kidney of goldfish (Carassius auratus, Linnaeus 1758): A light and confocal microscopy study Via histochem Acta Histochem. 2022 Mar 15;124(3):151876. doi: 10.1016/j.acthis.2022.151876. Online ahead of print. ABSTRACT Rodlet cells (RCs) have always been an enigma for scientists. RCs have been given a variety of activities over the years, including ion transport, osmoregulation, and sensory function. These cells, presumably as members of the granulocyte line, are present only in teleosts and play a role in the innate immune response. RCs are migratory cells found in a variety of or gans, including skin, vascular, digestive, uropoietic, reproductive, and respiratory systems, and present distinct physical properties that make them easily recognizable in tissues and organs. The development of RCs can be divided into four stages: granular, transitional, mature, and ruptured, having different morphological characteristics. Our study aims to characterize the different stages of these cells by histomorphological and histochemical techniques. Furthermore, we characterized these cells at all stages with peroxidase and fluorescence immunohistochemical techniques using different antibodies: S100, tubulin, α-SMA, piscidin, and for the first time TLR-2. From our results, the immunoreactivity of these cells to the antibodies performed may confirm that RCs play a role in fish defense mechanisms, helping to expand the state of the art on immunology and immune cells of teleosts. PMID:35303512 | DOI:10.1016/j.acthis.2022.151876 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.