RECIST 1.1—Update and clarification: From the RECIST committee

Publication date: Available online 14 May 2016
Source:European Journal of Cancer
Author(s): Lawrence H. Schwartz, Saskia Litière, Elisabeth de Vries, Robert Ford, Stephen Gwyther, Sumithra Mandrekar, Lalitha Shankar, Jan Bogaerts, Alice Chen, Janet Dancey, Wendy Hayes, F. Stephen Hodi, Otto S. Hoekstra, Erich P. Huang, Nancy Lin, Yan Liu, Patrick Therasse, Jedd D. Wolchok, Lesley Seymour
The Response Evaluation Criteria in Solid Tumours (RECIST) were developed and published in 2000, based on the original World Health Organisation guidelines first published in 1981. In 2009, revisions were made (RECIST 1.1) incorporating major changes, including a reduction in the number of lesions to be assessed, a new measurement method to classify lymph nodes as pathologic or normal, the clarification of the requirement to confirm a complete response or partial response and new methodologies for more appropriate measurement of disease progression. The purpose of this paper was to summarise the questions posed and the clarifications provided as an update to the 2009 publication.



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