Treatment with direct-acting anitiviral agents has revolutionized the treatment of chronic HCV infection. In the near future, these novel therapies will have a profound impact on HCV prevalence and HCV-induced carcinogenesis. In this review, we discuss treatment options of HCV patients with both compensated and decompensated cirrhosis as well as HCV patients in pre- and post-transplantation settings with a focus on the currently available data on HCC development in these patient populations
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