Randomized, double-blind, phase III trial of palonosetron versus granisetron in the triplet regimen for preventing chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy: TRIPLE study

This paper reports the result of the first phase III study of comparing the efficacy of first- and second-generation 5-HT3 receptor antagonists, palonosetron and granisetron, in the triplet regimen with dexamethasone and aprepitant for preventing chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy.

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