The World's First Single-Room Proton Therapy Facility - Two-Year Experience

Publication date: Available online 9 July 2016
Source:Practical Radiation Oncology
Author(s): Jessika Contreras, Tianyu Zhao, Stephanie Perkins, Baozhou Sun, Sreekrishna Goddu, Sasa Mutic, Beth Bottani, Sharon Endicott, Jeff Michalski, Clifford Robinson, Christina Tsien, Jiayi Huang, Benjamin W. Fischer-Valuck, Dennis Hallahan, Eric Klein, Jeffrey Bradley
PurposeA review of our 2-year experience with the first single-gantry proton therapy (PT) system.Methods and Materials.All patients were consented to participate on an IRB-approved prospective patient registry between 12/2013 and 12/2015. PT was delivered in a single room facility using a synchrocyclotron with proton beam energy of 250MeV. The dataset was interrogated for demographics, diagnosis, treatment modality, and clinical trial involvement. Cases were classified as simple or complex based on fields used and immobilization. The volume of photon patients treated in our department was collected between 1/2011 and 12/2015 to evaluate the impact of PT on our photon patient volume.ResultsA total of 278 patients were treated with PT, including 228 (82%) adults and 50 (18%) pediatric cases. PT patients traveled a mean distance of 83.3miles compared to 47.4miles for photon patients queried in 2015. Rationale for treatment included re-irradiation (20%), involvement in prospective clinical trial (14%), and proximity to critical structures to maximally spare organs at risk (66%). Forty patients were enrolled on 5 adult and 3 pediatric prospective clinical trials. The most common histologies treated were glioma (27%) and non-small cell lung cancer (18%) in adults, and medulloblastoma (22%) and low-grade glioma (24%) in pediatric patients. Prostate cancer comprised 6% of PT. Complex cases comprised 45% of our volume. Our photon patient volume increased yearly between 2011–2015, with 2780 patients completing photon treatment in 2011 and 3385 patients in 2015. PT comprised 4% of overall patients treated with external beam radiation.ConclusionsThe installation of our single gantry proton facility has expanded the treatment options within our cancer center, helping to increase the number of patients we see. Patients travel from twice as far away to receive this treatment, many for typical proton therapy indications such as pediatrics or to participate in prospective clinical trials.



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