3-D View of Mutations May Identify Potential Targets for Cancer Drugs

A new computational tool may help expand the known number of mutations in cancer cells that could be targeted with new or existing drugs.

Researchers recently reported that the tool, called HotSpot3D, allowed them to model how genetic mutations change the ways proteins function and interact with each other to potentially drive cancer. It also helped them identify more than 800 novel mutations that potentially could be targeted with existing drugs. 

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