The tumor genome in human immunodeficiency virus–related head and neck cancer: Exploitable targets?

In a small cohort of human immunodeficiency virus–related head and neck cancers, the majority are demonstrated to bear mutations in head and neck cancer–relevant genes, with some similarities to genomic profiles for human immunodeficiency virus–unrelated head and neck cancers. Although gene panels are not definitive for mutational signatures, the pattern of mutations is consistent with mutational signatures associated with the activity of the virally responsive APOBEC gene editing proteins. See also pages 000-000.

from Cancer via ola Kala on Inoreader http://ift.tt/2znweeO
via IFTTT