Fertility management for malignant ovarian germ cell tumors patients

Publication date: December 2017
Source:Critical Reviews in Oncology/Hematology, Volume 120
Author(s): Chiara Di Tucci, Assunta Casorelli, Elisa Morrocchi, Innocenza Palaia, Ludovico Muzii, Pierluigi Benedetti Panici
Malignant Germ Cell Tumors have primarily affecting adolescents and young adults. In advanced disease, greater than 70% of patients can be cured with standard chemotherapy regimens and fertility-sparing surgery appears to be safe with excellent survival after long-term follow-up.Due to their rarity, follow up and fertility management is largely based on trials of epithelial ovarian cancer or on few small studies.We report a review of the literature studies about the assessment, the monitoring and the treatment of fertility for Malignant Germ Cell Tumors as pratical guidelines for management of fertility in these patients.



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