Ribociclib Extends Survival in HR+ Breast Cancer [News in Brief]

Adding the CDK4/6 inhibitor ribociclib to standard first-line endocrine therapy significantly prolonged survival in premenopausal and perimenopausal women with advanced HR-positive, HER2-negative breast cancer enrolled in the MONALEESA-7 trial. This is the first definitive evidence that CDK4/6 inhibitor–based therapy is effective for first-line treatment of premenopausal and perimenopausal women.

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