Glucose Metabolism in Cancer: The Saga of Pyruvate Kinase Continues

Publication date: 12 March 2018
Source:Cancer Cell, Volume 33, Issue 3
Author(s): Annamarie E. Allen, Jason W. Locasale
Altered glucose metabolism is common in cancer. In this issue of Cancer Cell, Morita et al. report new mouse models that express specific isoforms of pyruvate kinase to study glycolysis in tumors. They report several unanticipated findings that challenge current ideas in cancer metabolism.

Teaser

Altered glucose metabolism is common in cancer. In this issue of Cancer Cell, Morita et al. report new mouse models that express specific isoforms of pyruvate kinase to study glycolysis in tumors. They report several unanticipated findings that challenge current ideas in cancer metabolism.


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