Screening for human papillomavirus-driven oropharyngeal cancer: Considerations for feasibility and strategies for research

The incidence and burden of human papillomavirus (HPV)-driven oropharyngeal cancer (OPC) is expected to increase for decades, thus motivating discussions regarding possibilities for screening. This article addresses issues related to the validity and timeliness of screening for HPV-driven OPC, and raises important questions, highlights deficits and confusion in the existing literature, and proposes needed steps in the research agenda.

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