Therapeutic Effect of Steroids on Vestibular Neuritis: Systematic Review and Meta‐analysis

xlomafota13 shared this article with you from Inoreader Therapeutic Effect of Steroids on Vestibular Neuritis: Systematic Review and Meta‐analysis Via Clinical Otolaryngology ABSTRACT Objectives The present meta-analysis sought to assess further evidence for the efficacy of steroids in vestibular neuritis (VN). Methods The PubMed, EMBASE and Cochrane Library databases were searched through August 30, 2019. The main outcome measure was dizziness handicap inventory (DHI) and secondary outcomes included complete caloric recovery and improvement of canal paresis (CP). The follow-up times were divided into short, mid, and long-term. Results Among 276 records identified, 5 studies (n = 253) were included in the analysis. The therapeutic effect of steroid on VN was confirmed (Hedges' g = 0.172, 95% CI 0.05 to 0.30, p = .006). Although there was no significant difference between steroids and control in the DHI score (Hedges' g = -0.323, 95% CI -0.533 to -0.113, p < 0.01), significant effect was seen on complete caloric recovery and improvement in CP (Hedges' g = 0.364, 95% CI 0.18 to 0.55, p < 0.0001; Hedges' g = 0.592, 95% CI 0.32 to 0.59, p < .0001) Conclusions The results suggest that corticosteroids have an effect on the results of caloric tests for VN recovery, especially in long-term follow-up. However, in the term of dizziness handicap, we did not find any evidence of positive effect of corticosteroid. More data are required before recommendations can be made regarding management in patients on corticosteroids. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.