B Cells Promote Pancreatic Tumorigenesis [In the Spotlight]

Summary: Three recent studies, approaching the question from different angles and using different and/or overlapping models, provide compelling evidence for the involvement of tumor-infiltrating B cells in the initiation and progression of pancreatic ductal adenocarcinoma. These studies highlight the need for a better understanding of pancreatic tumor–immune system interactions and the immunologic mechanisms that promote or inhibit tumorigenesis, paving the way for better treatment strategies. Cancer Discov; 6(3); 230–2. ©2016 AACR.

See related article by Pylayeva-Gupta et al., p. 247.

See related article by Lee et al., p. 256.

See related article by Gunderson et al., p. 270.

from Cancer via ola Kala on Inoreader http://ift.tt/1TYOVwH
via IFTTT