A prognostic regulatory pathway in stage I Epithelial Ovarian Cancer: new hints for the poor prognosis assessment

Currently, the therapies in stage I EOC are assigned following the clinical and histopathological risk factors. Although helpful, their sensitivity and specificity in the risk definition are completely unsatisfactory. We propose a prognostic pathway of 26 miRNAs and genes. The expressions of these elements can be used to define a patient-specific index able to improve the risk prediction at the time of diagnosis.

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