Is it best to expect the worst? Influence of patients' side-effect expectations on endocrine treatment outcome in a 2-year prospective clinical cohort study

Breast cancer patients' side-effect expectations prospectively influenced the incidence of side-effects, quality of life, and adherence during 2 years of endocrine treatment. The unique impact of expectations on long-term tolerability is important, because expectations can be psychologically modified and become a therapeutic target to prevent nocebo-related effects and non-adherence.

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