[Correspondence] Risk of cancer in patients with polycystic kidney disease – Authors’ reply

We thank Leano Violo and colleagues and Francois Cachat and Raffaele Renella for their comments. We agree that we are not able to clarify the effect of chronic kidney disease on the cancer risk without renal function data such as serum creatinine or glomerular filtration rate, and we addressed this limitation in the Article. By retrieving data from inpatient claims and analysing these data in multivariable models we attempted to attenuate the potential effect of associated confounders. Our previous study of a cohort of patients with chronic kidney disease made use of data from the Taiwan National Health Insurance Research Database (NHIRD).

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