[Correspondence] Risk of cancer in patients with polycystic kidney disease

Tung-Min Yu and colleagues1 report an increased susceptibility to colon, liver, and kidney cancer in patients with autosomal dominant polycystic kidney disease (ADPKD) before receiving renal replacement therapy, when compared with patients without the disease but with a similar (or no) degree of renal impairment. Large studies have shown an excess risk of cancer in patients with chronic kidney disease, end-stage renal disease, or those on renal replacement therapy. Available data for cancer incidence in patients with ADPKD on dialysis, or after transplantation, show an increased risk of neoplasms, mostly skin and kidney, when compared with the general population, but not to other patients on renal replacement therapy without ADPKD.

http://ift.tt/2eO9vBy