An Alternative Sugar Fuels AML

Publication date: 14 November 2016
Source:Cancer Cell, Volume 30, Issue 5
Author(s): Rob A. Cairns, Tak W. Mak
Although altered glucose metabolism is a well-studied feature of malignant cells, little is known about the direct metabolism of fructose. In this issue of Cancer Cell, Chen et al. report that AML cells consume fructose and use it to maintain viability, especially when glucose is scarce.

Teaser

Although altered glucose metabolism is a well-studied feature of malignant cells, little is known about the direct metabolism of fructose. In this issue of Cancer Cell, Chen et al. report that AML cells consume fructose and use it to maintain viability, especially when glucose is scarce.


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