Controversies in Postoperative Irradiation of Oropharyngeal Cancer After Transoral Surgery

Publication date: Available online 11 May 2017
Source:Surgical Oncology Clinics of North America
Author(s): Sue S. Yom, Jon Mallen-St. Clair, Patrick K. Ha

Teaser

Transoral surgery (TOS) is a novel technology whose adoption is expanding in the United States and other countries. TOS offers the possibility of a minimally invasive surgical approach to head and neck cancers. Its most frequent application has been in oropharyngeal cancers (OPC), of which most are associated with human papillomavirus (HPV). For HPV-associated OPC, where high response and survival rates are expected, deintensification of standard therapy is a major area of clinical research. In HPV-OPC, traditional pathologic risk factors indicating a need for adjuvant radiation or chemoradiation may not apply as strongly.


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