Abstract It is well recognized that poor muscle function and poor physical performance are strong predictors of clinically relevant adverse events in older people. Given the large number of approaches to measure muscle function and physical performance, clinicians often struggle to choose a tool that is appropriate and validated for the population of older people they deal with. In this paper, an overview of different methods available and applicable in clinical settings is proposed....
Wed Apr 10, 2019 03:00
Abstract Purpose Nanoparticles of human serum albumin (HSA) prepared using a desolvation method possess sizes suitable for tumor accumulation. Here, we report on an investigation of the anti-tumor effects and biodistribution of doxorubicin–HSA nanoparticles in vitro and in vivo. Methods The cytotoxicity of nanoparticles was evaluated in 2D and 3D colon 26...
Wed Apr 10, 2019 03:00
Abstract Background To evaluate the efficacy of docetaxel, cisplatin, and 5-fluorouracil as combination chemoradiotherapy (DCF-RT) for cervical esophageal cancer (CEC), we performed a retrospective analysis of CEC patients treated by DCF-RT at a single institution. Methods We conducted a single-center retrospective study. Twenty-one patients with CEC who...
Tue Apr 09, 2019 03:00
Abstract Purpose Several retrospective studies have shown that the antitumor efficacy of capecitabine-containing chemotherapy decreases when co-administered with a proton pump inhibitor (PPI). Although a reduction in capecitabine absorption by PPIs was proposed as the underlying mechanism, the effects of PPIs on capecitabine pharmacokinetics remain unclear. We prospectively examined the effects of rabeprazole on the pharmacokinetics of...
Tue Apr 09, 2019 03:00
Abstract Purpose In this study our aim was to compare efficacy and toxicity profiles of two different schedule of carboplatin-paclitaxel regimen in elderly advanced non-small cell lung cancer (NSCLC) patients. Methods Data from the charts of 59 elderly patients with metastatic NSCLC, treated with weekly paclitaxel combined with two different schedule of carboplatin were...
Tue Apr 09, 2019 03:00
Abstract Metropolitan areas may suffer with increase of air pollution due to the growth of urbanization, transportation, and industrial sectors. The Metropolitan Area of Vitória (MAV) in Brazil is facing air pollution problems, especially because of the urbanization of past years and of having many industries inside the metropolitan area. Developing air quality system is crucial to understand the air pollution mechanism over these areas. However, having a good input dataset for...
Wed Apr 10, 2019 03:00
Abstract Sulfur-doped activated carbons (SACs) with high sulfur content and large specific surface area were synthesized from polythiophene for acetone removal. The sulfur content of carbons (3.10–8.43 at.%) could be tunable by adjusting the activation temperature. The BET surface area and pore volume of the obtained samples were 916–2020 m2 g−1 and 0.678–1.100 cm3 g−1, with a significant proportion of microporosity (up to 84% and 72% for BET surface area and pore volume, respectively)....
Wed Apr 10, 2019 03:00
Abstract This study applies asymmetric causality to renewable energy (REC), carbon dioxide emissions (CE), and real GDP using non-linear broadcasting between these variables through the non-linear autoregressive distributed lag model (NARDL) to examine the short- and long-run asymmetries in the inconsistency of greenhouse gas emissions among the variables and to unpack the asymmetric causality of selective variables through positive and negative shocks for time series data from...
Wed Apr 10, 2019 03:00
Abstract As an important role in economic development in China, industrial parks have consumed plenty of energy, while emitting enormous air pollutants and discharging large quantities of waste heat. Energy cascade utilization is an effective way to improve the energy efficiency of industrial parks. The objective of this study was to assess the co-benefits of energy cascade utilization, including the energy savings potential, reduction potential of air pollutants, and air quality...
Wed Apr 10, 2019 03:00
Abstract The essential oil was extracted from the roots of Valeriana officinalis L. by hydrodistillation. The qualitative and quantitative analysis of its chemical constituents was conducted on GC-MS and GC-FID in this study. Seventeen compounds were detected and the major constituents included bornyl acetate (48.2%) and camphene (13.8%). The toxic and repellent effects of the essential oil and its two major constituents were evaluated on Liposcelis bostrychophila and Tribolium...
Wed Apr 10, 2019 03:00
Abstract The aim of the present study was to scrutiny the impact of pulsed electric field (PEF) as a pre-treatment method on the convective drying kinetics, cell disintegration, colours and microstructural changes of fresh plums. In this study, the PEF intensities of 1–3 kV/cm, pulses number 30 and 70 °C drying temperature was applied to detect the drying kinetics. The specific energy consumption generated by PEF treatment was 10–90 kJ/kg. It was explored that the cell disintegration...
Wed Apr 10, 2019 03:00
Abstract Topical treatment of fungal infections has several superiorities over oral treatment. However, the greatest challenge for dermal delivery is the stratum corneum which is considered an effective barrier for penetration of most antifungal drugs into deeper skin layers. Terconazole (Tr), which is the first marketed triazole antifungal, was reported to be one of the most active azoles against vaginal candidiasis. Nevertheless, our work group is the first to investigate the...
Wed Apr 10, 2019 03:00
Wed Apr 10, 2019 03:00
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