To the Editor Knoops and Bastin focus on an important population of patients who have hematological malignant neoplasms with uncertain prognoses and a high chance of suffering from distressing symptoms during the course of their cancer and treatment. Their description of "escalation of commitment" is a fitting paradigm in this population and with this patient-physician dyad. They recommend several strategies to defend against this bias, including clinician self-reflection, discussing risk of treatment failure and alternative approaches even before starting disease modifying therapy, and finally involving a third party such as a palliative care specialist.
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