Πέμπτη 5 Ιουλίου 2018

Genotoxic Lemons Become Epigenomic Lemonade

Publication date: 5 July 2018

Source: Cell Stem Cell, Volume 23, Issue 1

Author(s): Stefan F. Cordes, Cynthia E. Dunbar

Active regulatory elements in hematopoietic stem cells (HSCs) are incompletely characterized, since extant approaches immunophenotypically define and isolate rare HSCs. In the current issue of Cell Stem Cell, Wünsche et al. (2018) use γ-retroviral insertion sites from a human gene therapy trial to identify the active enhancer landscape of functionally characterized HSCs.



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