Philadelphia chromosome-positive lymphoblastic lymphoma—Is it rare or underdiagnosed?

Publication date: Available online 15 June 2018

Source: Hematology/Oncology and Stem Cell Therapy

Author(s): Ahmad Alshomar, Riad El Fakih

Abstract

Lymphoblastic lymphomas (LBLs) are neoplasms of precursor B and T cells; they are considered in the same spectrum as precursor B and T cell acute lymphoblastic leukemia (ALL). The World Health Organization classification classifies both LBL and ALL as one disease entity. While chromosome abnormalities are well defined with all of their therapeutic and prognostic implications in ALL, these are not well studied in LBL. Here, we describe a case of Philadelphia chromosome-positive LBL and review the available literature regarding this entity.

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