Πέμπτη 5 Ιουλίου 2018

Postmitotic Fate Refinement in the Subplate

Publication date: 5 July 2018

Source: Cell Stem Cell, Volume 23, Issue 1

Author(s): Mohammed A. Mostajo-Radji, Alex A. Pollen

How is the astonishing diversity of cortical neurons specified? In this issue of Cell Stem Cell, Ozair et al. (2018) leverage hPSC neural differentiation to show that projection neurons undergo prolonged sojourns in the subplate before migrating to deep layers, suggesting that pausing in the subplate may enable integration of intrinsic and extrinsic cues during postmitotic fate refinement.



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