Absence of CMV viremia in high-grade glioma patients under low dosage glucocorticoid treatment

Cytomegalovirus (CMV), a life-threatening infectious pathogen in immunosuppressed patients, is a hot topic in the evolution and treatment of high-grade gliomas. Goerig et al¹ showed recently that the reactivation of CMV is common and associated with radiotherapy (RT) and the dosage of dexamethasone intake administered before or during RT. In this study we attempted to validate this finding by screening high-grade glioma patients (n = 29) for presence of CMV viremia and anti-CMV immunoglobulins in relation to selected clinical information.

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