[Correspondence] Predictive gene-expression score for follicular lymphoma

In a recent article, Sarah Huet and colleagues1 analysed the prognostic value of the expression of a large set of genes in patients with follicular lymphoma. After a careful and rigorous process of curation and selection (on the basis of the correlation between the expression of each gene and progression-free survival), the authors developed a gene-expression signature score based on the expression of 23 genes. This study provided invaluable data regarding the biology of malignant cells and the role of the microenvironment in follicular lymphoma in the immunochemotherapy era.

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