Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1185-9283 Aims Our study aimed to investigate the role of long non-coding RNA ANRIL (lnc-ANRIL) knock-down in regulating cell activities, inflammation and downstream signaling pathways in mouse mesangial cellular diabetic nephropathy (DN) model. Methods The mouse mesangial cells (SV40-MES13 cells) were treated with ...
Wed Jul 29, 2020 02:00
Abstract Bradymyces oncorhynchi is a poorly known melanised fungal species that has been isolated only from a hyperaemic focus near the enlarged spleen of a rainbow trout. Although the pathogenicity of this species to fish is suspected, it has not been fully confirmed. Four laboratory experiments were conducted to test the effect of the fungus on the health of rainbow trout fingerlings. Mycelia were cultivated under different conditions to increase inoculum variability and to...
Wed Jul 29, 2020 03:00
Geological evidence suggests the known dinosaur groups diverged early on, supporting the traditional dinosaur family tree.
Wed Jul 29, 2020 21:14
A new study confirms that while the eastern and western butterflies fly differently, they are genetically the same.
Wed Jul 29, 2020 19:44
Abstract Purpose We aimed to evaluate the clinical efficacy and safety of lenvatinib in patients with advanced anaplastic thyroid cancer (ATC) in real-world practice. Methods This multicenter, retrospective cohort study included 14 patients with advanced ATC who received lenvatinib. We evaluated the response rate according to RECIST. ...
Wed Jul 29, 2020 03:00
Mucosal Immunology, Published online: 29 July 2020; doi:10.1038/s41385-020-0329-zIL-17A moonlighting in lung type 2 immunity
Wed Jul 29, 2020 03:00
The coronavirus SARS-CoV-2 at the origin of COVID-19 shares more than 70% genetic similarity with SARS-CoV-1 that was at the origin of 2003 SARS. Infection-associated symptoms are very similar between SARS and COVID-19 diseases and are the same as community-acquired pneumonia symptoms. Antibiotics were empirically given to SARS patients in the early stages of the pathology whereas a different strategy has been decided in the management of COVID-19 pandemic with a worldwide shutdown. The cytokine...
Tue Jul 28, 2020 11:55
OBJECTIVE: Since December 2019, a novel coronavirus disease 2019 (COVID-19) broke out in Wuhan, China, which has rapidly spread from China to at least 200 countries abroad. COVID-19 was issued a global outbreak and pandemic by the World Health Organization with more than 3 million confirmed cases by May 31, 2020. So far more than ten thousand severe and critically ill patients and hospital-related infection with COVID-19 have been reported with more than four thousand deaths in China. There is a...
Tue Jul 28, 2020 11:55
Publication date: Available online 29 July 2020Source: Behavioural Brain ResearchAuthor(s): Lei Wang, Shuzhen Zuo, Yudian Cai, Boqiang Zhang, Huimin Wang, Yong-di Zhou, Sze Chai Kwok
Wed Jul 29, 2020 18:32
Background: Data on exercise training in chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary endarterectomy (PEA) as well as data on clinical and haemodynamic changes shortly after PEA are lacking. Objective: The objective of this prospective study was to analyse the safety, feasibility, and the effectiveness of combined supervised inpatient rehabilitation in patients with CTEPH directly after PEA. Methods: CTEPH patients started a 19-week rehabilitation program (3 weeks as inpatients...
Wed Jul 29, 2020 14:07
Ultrasound-guided needle aspiration via the esophagus using the endobronchial endoscope (EUS-B-FNA) is increasingly being performed by the pulmonologist for the diagnosis of lung cancer, but we have little experience and data available in the literature especially with respect to staging of the disease. We present 2 cases of EUS-B-guided aspiration of malignant pericardial effusion performed in the same setting as bronchoscopy and endobronchial ultrasound. No complications were observed. We conclude...
Wed Jul 29, 2020 10:10
We report a case of a rapidly fatal postlaparoscopic cholecystectomy liver infection from the rarely isolated species Clostridium butyricum. Liver examination at autopsy showed cystic spaces, necrosis, and spore-forming Gram-positive rods. 16sRNA gene sequencing of the cystic liver tissue identified the organism as C. butyricum.
Wed Jul 29, 2020 08:50
Oncogenesis, Published online: 29 July 2020; doi:10.1038/s41389-020-00254-2The identification of nuclear αvβ3 integrin in ovarian cancer: non-paradigmal localization with cancer promoting actions
Wed Jul 29, 2020 03:00
Publication date: Available online 29 July 2020Source: CortexAuthor(s): Sophie-Marie Rostalski, Catarina Amado, Gyula Kovács, Daniel Feuerriegel
Wed Jul 29, 2020 16:42
Publication date: Available online 29 July 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Mark Sherer, Douglas I. Katz, Yelena G. Bodien, David B. Arciniegas, Cady Block, Sonja Blum, Matt Doiron, Kim Frey, Joseph T. Giacino, Min Jeong P. Graf, Brian Greenwald, Flora M. Hammond, Kathleen Kalmar, Jacob Kean, Marilyn F. Kraus, Risa Nakase- Richardson, Shital Pavawalla, Amy Rosenbaum, Donald T. Stuss, Stuart A. Yablon
Wed Jul 29, 2020 15:52
This study focused on the beneficial effects of Capparis spinosa (CS) treatment on the steatohepatitis induced by the administration of a high-fat emulsion in rats. Changes of hepatic expression and secretion of ...
Tue Jul 28, 2020 03:00
This study is the first concerted effort to ascertain factor structure of EPDS using evidence based analytical techniques. It is the most widely used scale for assessing postpartum depression in Turkey, and ye...
Tue Jul 28, 2020 03:00
Maintenance treatment with macrolide antibiotics has shown to be effective in reducing exacerbations in COPD patients. A major concern with prolonged treatment with antibiotics is the development of bacterial ...
Tue Jul 28, 2020 03:00
Related Articles Assessment of the risk of malnutrition due to aspiration pneumonia and oral feeding difficulty. Nutr Hosp. 2020 Jul 28;: Authors: Sato S, Hidetoshi T Abstract INTRODUCTION: many patients with acute-phase swallowing disorders experience malnutrition, which can be caused by oral intake difficulties. Many diseases can cause swallowing difficulties such as aspiration pneumonia, and it is, therefore, necessary to consider the risk...
Wed Jul 29, 2020 14:33
Abstract Introduction This study aimed to evaluate the long‐term outcome of microwave ablation (MWA) of early‐stage non‐small cell lung cancer (NSCLC), including response to treatment and survival. Methods This retrospective study was conducted on consecutive patients who underwent computed tomography‐guided MWA of early‐stage NSCLC (no evidence of nodal or distant metastasis) from November 2010 to December 2014 at our institution. Data were collected from systematic review of patient charts...
Tue Jul 28, 2020 14:00
Publication date: Available online 28 July 2020Source: Magnetic Resonance ImagingAuthor(s): Roshan Samuel Livingstone, Abel Juhan Thomas, Riddhi Dasgupta, Shajith Anoop, Mathews Edatharayil Kurian, Meredith Hawkins, Nihal Thomas
Wed Jul 29, 2020 14:03
Medical cannabis (MC) is currently being used as an adjunct to opiates given its analgesic effects and potential to reduce opiate addiction. This review assessed if MC used in combination with opioids to treat...
Tue Jul 28, 2020 03:00
Abstract Cuticular hydrocarbons (CHCs) are organic compounds found on the cuticles of all insects which can act as close‐contact pheromones, while also providing a hydrophobic barrier to water loss. Given their widespread importance in sexual behaviour and survival, CHCs have likely contributed heavily to the adaptation and speciation of insects. Despite this, the patterns and mechanisms of their diversification have been studied in very few taxa. Here, we perform the first study of CHC diversification...
Tue Jul 28, 2020 11:45
Tue Jul 28, 2020 11:07
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Tue Jul 28, 2020 08:31
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundBasal and squamous cell carcinomas represent the most common cancers in North America. Their management is an important issue.ObjectivesThe evaluation of cure rates of minimally invasive cutaneous carcinomas with curettage-cryosurgery compared to curettage-electrodesiccation, as well as the assessment of the aesthetic appearance of scars.MethodsThis prospective trial randomized 117 patients 1:1 to treatments of curettage-cryosurgery...
Tue Jul 28, 2020 08:17
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