IJMS, Vol. 21, Pages 5380: A Rapid, Simple, Inexpensive, and Mobile Colorimetric Assay COVID-19-LAMP for Mass On-Site Screening of COVID-19 International Journal of Molecular Sciences doi: 10.3390/ijms21155380 Authors: Franklin Wang-Ngai Chow Tony Tat-Yin Chan Anthony Raymond Tam Suhui Zhao Weiming Yao Joshua Fung Flora Ka-Kei Cheng George Chi-Shing Lo Stella Chu Kam Leng Aw-Yong James Yat-Man Tang Chi-Ching Tsang Hayes Kam-Hei Luk Antonio Cheuk-Pui Wong...
IJMS, Vol. 21, Pages 5384: Exosomal MicroRNAs in Pregnancy Provides Insight into a Possible Cure for Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21155384 Authors: Preenan Pillay Kogi Moodley Manu Vatish Jagidesa Moodley The biological links between cancer and pregnancy are of recent interest due to parallel proliferative, immunosuppressive and invasive mechanisms between tumour and trophoblast development. Therefore, understanding “cancer-like”...
IJMS, Vol. 21, Pages 5382: Regulation of Filaggrin, Loricrin, and Involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: Pathogenic Implications in Atopic Dermatitis International Journal of Molecular Sciences doi: 10.3390/ijms21155382 Authors: Masutaka Furue Atopic dermatitis (AD) is an eczematous, pruritic skin disorder with extensive barrier dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction correlates with the downregulation of barrier-related...
IJMS, Vol. 21, Pages 5379: Inactivation of Endothelial ADAM17 Reduces Retinal Ischemia-Reperfusion Induced Neuronal and Vascular Damage International Journal of Molecular Sciences doi: 10.3390/ijms21155379 Authors: Diana R Gutsaeva Lamiaa Shalaby Folami L Powell Menaka C Thounaojam Hossameldin Abouhish Sara A Wetzstein Ravirajsinh N Jadeja Hang Fai Kwok Pamela M Martin Manuela Bartoli Retinal ischemia contributes to visual impairment in ischemic retinopathies....
IJMS, Vol. 21, Pages 5381: miR-142-3p Expression Is Predictive for Severe Traumatic Brain Injury (TBI) in Trauma Patients International Journal of Molecular Sciences doi: 10.3390/ijms21155381 Authors: Cora Rebecca Schindler Mathias Woschek Jan Tilmann Vollrath Kerstin Kontradowitz Thomas Lustenberger Philipp Störmann Ingo Marzi Dirk Henrich Background: Predictive biomarkers in biofluids are the most commonly used diagnostic method, but established markers in trauma...
IJMS, Vol. 21, Pages 5383: Bacteroides fragilis Enterotoxin Induces Sulfiredoxin-1 Expression in Intestinal Epithelial Cell Lines Through a Mitogen-Activated Protein Kinases- and Nrf2-Dependent Pathway, Leading to the Suppression of Apoptosis International Journal of Molecular Sciences doi: 10.3390/ijms21155383 Authors: Jong Ik Jeon Jun Ho Choi Keun Hwa Lee Jung Mogg Kim Enterotoxigenic Bacteroides fragilis is a causative agent of colitis and secrets enterotoxin (BFT), leading...
IJMS, Vol. 21, Pages 5377: The Role of the Epididymis and the Contribution of Epididymosomes to Mammalian Reproduction International Journal of Molecular Sciences doi: 10.3390/ijms21155377 Authors: Emma R. James Douglas T. Carrell Kenneth I. Aston Timothy G. Jenkins Marc Yeste Albert Salas-Huetos It is well-established that testicular spermatozoa are immature and acquire motility and fertilization capabilities during transit throughout the epididymis. The epididymis is...
IJMS, Vol. 21, Pages 5378: Molecular Mechanisms Underlying Hepatocellular Carcinoma Induction by Aberrant NRF2 Activation-Mediated Transcription Networks: Interaction of NRF2-KEAP1 Controls the Fate of Hepatocarcinogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21155378 Authors: Effi Haque M. Rezaul Karim Aamir Salam Teeli Magdalena Śmiech Paweł Leszczynski Dawid Winiarczyk Emil D. Parvanov Atanas G. Atanasov Hiroaki Taniguchi NF-E2-related...
IJMS, Vol. 21, Pages 5376: Life and Death of Fungal Transporters under the Challenge of Polarity International Journal of Molecular Sciences doi: 10.3390/ijms21155376 Authors: Sofia Dimou George Diallinas Eukaryotic plasma membrane (PM) transporters face critical challenges that are not widely present in prokaryotes. The two most important issues are proper subcellular traffic and targeting to the PM, and regulated endocytosis in response to physiological, developmental, or stress...
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IJNS, Vol. 6, Pages 59: The Early History of PKU International Journal of Neonatal Screening doi: 10.3390/ijns6030059 Authors: Louis I. Woolf John Adams The story of phenylketonuria (PKU) started in 1934 with Asbjørn Følling’s examination of two mentally retarded siblings from a Norwegian family. However, if their mother had not been so persistent in her search for somebody who could give her a reason why both her children were retarded, Asbjørn...
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JCM, Vol. 9, Pages 2429: Prevalence and Predictive Value of Anemia and Dysregulated Iron Homeostasis in Patients with COVID-19 Infection Journal of Clinical Medicine doi: 10.3390/jcm9082429 Authors: Bellmann-Weiler Lanser Barket Rangger Schapfl Schaber Fritsche Wöll Weiss Infections with SARS-CoV-2 can result in severe clinical manifestations. As such patients present with systemic inflammation, we studied the prevalence and predictive value of anemia...
JCM, Vol. 9, Pages 2428: Prediction of Function in ABCA4-Related Retinopathy Using Ensemble Machine Learning Journal of Clinical Medicine doi: 10.3390/jcm9082428 Authors: Müller Treis Odainic Pfau Herrmann Tufail Holz Full-field electroretinogram (ERG) and best corrected visual acuity (BCVA) measures have been shown to have prognostic value for recessive Stargardt disease (also called “ABCA4-related retinopathy”). These functional tests may...
JCM, Vol. 9, Pages 2427: Impact of Lymphadenectomy on Survival of Patients with Serous Advanced Ovarian Cancer After Neoadjuvant Chemotherapy: A French National Multicenter Study (FRANCOGYN) Journal of Clinical Medicine doi: 10.3390/jcm9082427 Authors: Virginie Bund Lise Lecointre Michel Velten Lobna Ouldamer Sofiane Bendifallah Martin Koskas Pierre-Adrien Bolze Pierre Collinet Geoffroy Canlorbe Cyril Touboul Cyrille Huchon Charles Coutant Emilie Faller...
JCM, Vol. 9, Pages 2426: Sex-Specific Prognostic Implications in Dilated Cardiomyopathy After Left Ventricular Reverse Remodeling Journal of Clinical Medicine doi: 10.3390/jcm9082426 Authors: Antonio Cannata Paolo Manca Vincenzo Nuzzi Caterina Gregorio Jessica Artico Piero Gentile Carola Pio Loco Federica Ramani Giulia Barbati Marco Merlo Gianfranco Sinagra Background. Women affected by Dilated Cardiomyopathy (DCM) experience better outcomes compared to...
JCM, Vol. 9, Pages 2423: T Helper Cell Infiltration in Osteoarthritis-Related Knee Pain and Disability Journal of Clinical Medicine doi: 10.3390/jcm9082423 Authors: Timo Albert Nees Nils Rosshirt Jiji Alexander Zhang Hadrian Platzer Reza Sorbi Elena Tripel Tobias Reiner Tilman Walker Marcus Schiltenwolf Hanns-Martin Lorenz Theresa Tretter Babak Moradi Sébastien Hagmann Despite the growing body of literature demonstrating a crucial role of T helper...
JCM, Vol. 9, Pages 2424: Neurologic Safety of Etomidate-Based Sedation during Upper Endoscopy in Patients with Liver Cirrhosis Compared with Propofol: A Double-Blind, Randomized Controlled Trial Journal of Clinical Medicine doi: 10.3390/jcm9082424 Authors: Jang Han Jung Bomi Hyun Jin Lee Dong Hee Koh Jung Hee Kim Se Woo Park (1) Background: Although etomidate-based sedation is an effective and safe protocol in endoscopic procedures, there is a lack of evidence regarding...
JCM, Vol. 9, Pages 2425: Evaluate the Differences in CT Features and Serum IgG4 Levels between Lymphoma and Immunoglobulin G4-Related Disease of the Orbit Journal of Clinical Medicine doi: 10.3390/jcm9082425 Authors: Wei-Hsin Yuan Anna Fen-Yau Li Shu-Yi Yu Ying-Yuan Chen Chia-Hung Wu Hui-Chen Hsu Jiing-Feng Lirng Wan-You Guo Background: Benign immunoglobulin G4 (IgG4)-related orbital disease (IgG4-ROD)—characterized as tumors mimicking malignant orbital...
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JFMK, Vol. 5, Pages 56: Multifaceted Exercise Prescription in the Management of an Overhead Athlete with Suspected Distal Biceps Tendinopathy: A Case Report Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5030056 Authors: Cameron Holshouser Dhinu J. Jayaseelan Background and Purpose: Distal biceps brachii tendinopathy is an uncommon diagnosis. Various exercise prescriptions have demonstrated efficacy in the management of tendinopathy, although studies frequently...
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JPM, Vol. 10, Pages 75: The Identification of Novel Biomarkers Is Required to Improve Adult SMA Patient Stratification, Diagnosis and Treatment Journal of Personalized Medicine doi: 10.3390/jpm10030075 Authors: Piera Smeriglio Paul Langard Giorgia Querin Maria Grazia Biferi Spinal muscular atrophy (SMA) is currently classified into five different subtypes, from the most severe (type 0) to the mildest (type 4) depending on age at onset, best motor function achieved, and copy...
JPM, Vol. 10, Pages 74: The Viral Hypothesis in Alzheimer’s Disease: Novel Insights and Pathogen-Based Biomarkers Journal of Personalized Medicine doi: 10.3390/jpm10030074 Authors: Sean X Naughton Urdhva Raval Giulio M. Pasinetti Early diagnosis of Alzheimer’s disease (AD) and the identification of significant risk factors are necessary to better understand disease progression, and to develop intervention-based therapies prior to significant neurodegeneration. There is...
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Medicina, Vol. 56, Pages 381: Neutrophil-To-Lymphocyte Ratio and Systemic Immune-Inflammation Index—Biomarkers in Interstitial Lung Disease Medicina doi: 10.3390/medicina56080381 Authors: Victoria Maria Ruta Adina Milena Man Teodora Gabriela Alexescu Nicoleta Stefania Motoc Simina Tarmure Rodica Ana Ungur Doina Adina Todea Sorina Cezara Coste Dan Valean Monica Carmen Pop Background and objectives: The aims of the study were to evaluate the utility of neutrophil-to-lymphocyte...
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Medicines, Vol. 7, Pages 44: Genetic Alterations in Renal Cancers: Identification of The Mechanisms Underlying Cancer Initiation and Progression and of Therapeutic Targets Medicines doi: 10.3390/medicines7080044 Authors: Ugo Testa Elvira Pelosi Germana Castelli Renal cell cancer (RCC) involves three most recurrent sporadic types: clear-cell RCC (70–75%, CCRCC), papillary RCCC (10–15%, PRCC), and chromophobe RCC (5%, CHRCC). Hereditary cases account for about...
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Membranes, Vol. 10, Pages 170: Operating Conditions Optimization via the Taguchi Method to Remove Colloidal Substances from Recycled Paper and Cardboard Production Wastewater Membranes doi: 10.3390/membranes10080170 Authors: Mayko Rannany S. Sousa Jaime Lora-García María-Fernanda López-Pérez Asunción Santafé-Moros José M. Gozálvez-Zafrilla Optimization of the ultrafiltration (UF) process to remove colloidal substances from a paper mill’s treated effluent was investigated...
Membranes, Vol. 10, Pages 169: Diffusion Dialysis for Acid Recovery from Acidic Waste Solutions: Anion Exchange Membranes and Technology Integration Membranes doi: 10.3390/membranes10080169 Authors: Chengyi Zhang Wen Zhang Yuxin Wang Inorganic acids are commonly used in mining, metallurgical, metal-processing, and nuclear-fuel-reprocessing industries in various processes, such as leaching, etching, electroplating, and metal-refining. Large amounts of spent acidic liquids containing...
Membranes, Vol. 10, Pages 171: A Simple Method to Identify the Dominant Fouling Mechanisms during Membrane Filtration Based on Piecewise Multiple Linear Regression Membranes doi: 10.3390/membranes10080171 Authors: Hao Xu Kang Xiao Jinlan Yu Bin Huang Xiaomao Wang Shuai Liang Chunhai Wei Xianghua Wen Xia Huang Membrane fouling is a complicated issue in microfiltration and ultrafiltration. Clearly identifying the dominant fouling mechanisms during the filtration...
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Metabolites, Vol. 10, Pages 311: Multiblock Analysis to Relate Polyphenol Targeted Mass Spectrometry and Sensory Properties of Chocolates and Cocoa Beans Metabolites doi: 10.3390/metabo10080311 Authors: Noémie Fayeulle Sébastien Preys Jean-Michel Roger Renaud Boulanger Clotilde Hue Véronique Cheynier Nicolas Sommerer Chocolate quality is largely due to the presence of polyphenols and especially of flavan-3-ols and their derivatives that contribute to bitterness and...
Metabolites, Vol. 10, Pages 310: Effects of Water Deficit and Heat Stress on Nicotiana langsdorffii Metabolomic Pattern Modified by Insertion of rolD Gene from Agrobacterium rhizogenes Metabolites doi: 10.3390/metabo10080310 Authors: Elisa Scalabrin Marta Radaelli Gabriele Capodaglio Abiotic stresses are major factors that negatively affect plant growth and productivity. Plants have developed complex strategies to ensure their survival and reproduction under adverse conditions,...
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MPs, Vol. 3, Pages 53: Unexpectedly High Levels of Inverted Re-Insertions Using Paired sgRNAs for Genomic Deletions Methods and Protocols doi: 10.3390/mps3030053 Authors: Joseph Blayney Evangeline M. Foster Marta Jagielowicz Mira Kreuzer Matteo Morotti Katharina Reglinski Julie Huiyuan Xiao Philip Hublitz Use of dual sgRNAs is a common CRISPR/Cas9-based strategy for the creation of genetic deletions. The ease of screening combined with a rather high rate of success...
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Microorganisms, Vol. 8, Pages 1148: Probiotics for The Treatment of Overweight and Obesity In Humans—A Review of Clinical Trials Microorganisms doi: 10.3390/microorganisms8081148 Authors: Michał Wiciński Jakub Gębalski Jakub Gołębiewski Bartosz Malinowski The World Health Organization (WHO) reports that 400 million people are obese, and over 1.6 billion adults are overweight worldwide. Annually, over 2.8 million people die from obesity-related diseases. The incidence of overweight...
Microorganisms, Vol. 8, Pages 1150: Planctomycetes as a Vital Constituent of the Microbial Communities Inhabiting Different Layers of the Meromictic Lake Sælenvannet (Norway) Microorganisms doi: 10.3390/microorganisms8081150 Authors: Julia E. Storesund Anders Lanzèn Eva-Lena Nordmann Hilde Rief Armo Olga Maria Lage Lise Øvreås Meromictic lakes are permanently stratified lakes that display steep gradients in salinity, oxygen and sulphur compounds tightly linked to bacterial...
Microorganisms, Vol. 8, Pages 1149: Teff Type-I Sourdough to Produce Gluten-Free Muffin Microorganisms doi: 10.3390/microorganisms8081149 Authors: Cinzia Dingeo Graziana Difonzo Vito Michele Paradiso Carlo Giuseppe Rizzello Erica Pontonio The increasing number of persons following a gluten-free (GF) diet and the need for healthy and natural products are forcing researchers and industries to provide gluten-free products with high nutritional value. Here, a biotechnological...
Microorganisms, Vol. 8, Pages 1151: Discovery of Predictors of Mycoplasma hyopneumoniae Vaccine Response Efficiency in Pigs: 16S rRNA Gene Fecal Microbiota Analysis Microorganisms doi: 10.3390/microorganisms8081151 Authors: Peris M. Munyaka Fany Blanc Jordi Estellé Gaëtan Lemonnier Jean-Jacques Leplat Marie-Noëlle Rossignol Déborah Jardet Graham Plastow Yvon Billon Benjamin P. Willing Claire Rogel-Gaillard The gut microbiota comprises a large and diverse...
Microorganisms, Vol. 8, Pages 1146: Dynamics of the Honeybee (Apis mellifera) Gut Microbiota Throughout the Overwintering Period in Canada Microorganisms doi: 10.3390/microorganisms8081146 Authors: Naomie Bleau Sidki Bouslama Pierre Giovenazzo Nicolas Derome Microbial symbionts inhabiting the honeybee gut (i.e., gut microbiota) are essential for food digestion, immunity, and gut protection of their host. The taxonomic composition of the gut microbiota is dynamic throughout the...
Microorganisms, Vol. 8, Pages 1145: Fungal Community in Antarctic Soil Along the Retreating Collins Glacier (Fildes Peninsula, King George Island) Microorganisms doi: 10.3390/microorganisms8081145 Authors: Juliana Aparecida dos Santos Edenilson Meyer Lara Durães Sette Glacial retreat is one of the most conspicuous signs of warming in Antarctic regions. Glacier soils harbor an active microbial community of decomposers, and under the continuous retraction of glaciers, the soil starts...
Microorganisms, Vol. 8, Pages 1147: Characterization of Weissella koreensis SK Isolated from Kimchi Fermented at Low Temperature (around 0 °C) Based on Complete Genome Sequence and Corresponding Phenotype Microorganisms doi: 10.3390/microorganisms8081147 Authors: So Yeong Mun Hae Choon Chang This study identified lactic acid bacteria (LAB) that play a major role in kimchi fermented at low temperature, and investigated the safety and functionality of the LAB via biologic and genomic...
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Molecules, Vol. 25, Pages 3459: Synthesis, Characterization, Photoluminescence, Molecular Docking and Bioactivity of Zinc (II) Compounds Based on Different Substituents Molecules doi: 10.3390/molecules25153459 Authors: Rongping Liu Hao Yan Jinzhang Jiang Jiahe Li Xing Liang Dengfeng Yang Lixia Pan Tisan Xie Zhen Ma Six new zinc(II) complexes were prepared by the reaction of ZnBr2 or ZnI2 with 4′-(substituted-phenyl)-2,2′:6′,2′′-terpyridine...
Molecules, Vol. 25, Pages 3458: A Flavone-Based Solvatochromic Probe with A Low Expected Perturbation Impact on the Membrane Physical State Molecules doi: 10.3390/molecules25153458 Authors: Simona Concilio Miriam Di Martino Anna Maria Nardiello Barbara Panunzi Lucia Sessa Ylenia Miele Federico Rossi Stefano Piotto The study of the cell membrane is an ambitious and arduous objective since its physical state is regulated by a series of processes that guarantee its...
Molecules, Vol. 25, Pages 3457: Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry Molecules doi: 10.3390/molecules25153457 Authors: Chiara Brullo Federica Rapetti Olga Bruno The pyrazole nucleus has long been known as a privileged scaffold in the synthesis of biologically active compounds. Within the numerous pyrazole derivatives developed as potential drugs, this review is focused on molecules characterized by a urea function directly linked to the pyrazole nucleus...
Molecules, Vol. 25, Pages 3456: Study on the Adsorption of CuFe2O4-Loaded Corncob Biochar for Pb(II)
Molecules, Vol. 25, Pages 3456: Study on the Adsorption of CuFe2O4-Loaded Corncob Biochar for Pb(II) Molecules doi: 10.3390/molecules25153456 Authors: Tianci Zhao Xiaolong Ma Hao Cai Zichuan Ma Huifeng Liang A series of the magnetic CuFe2O4-loaded corncob biochar (CuFe2O4@CCBC) materials was obtained by combining the two-step impregnation of the corncob biochar with the pyrolysis of oxalate. CuFe2O4@CCBC and the pristine corncob biochar (CCBC) were characterized using XRD,...
Molecules, Vol. 25, Pages 3460: Differential Modulation of the Phospholipidome of Proinflammatory Human Macrophages by the Flavonoids Quercetin, Naringin and Naringenin Molecules doi: 10.3390/molecules25153460 Authors: Tiago A. Conde Luís Mendes Vítor M. Gaspar João F. Mano Tânia Melo M. Rosário Domingues Iola F. Duarte The immunomodulatory activity of flavonoids is increasingly appreciated. Macrophage phospholipids (PLs) play crucial roles in cell-mediated inflammatory...
Molecules, Vol. 25, Pages 3455: Stable Formulations of Peptide-Based Nanogels Molecules doi: 10.3390/molecules25153455 Authors: Elisabetta Rosa Carlo Diaferia Enrico Gallo Giancarlo Morelli Antonella Accardo Recently, nanogels have been identified as innovative formulations for enlarging the application of hydrogels (HGs) in the area of drug delivery or in diagnostic imaging. Nanogels are HGs-based aggregates with sizes in the range of nanometers and formulated in order to...
Molecules, Vol. 25, Pages 3454: Reflectance Spectroscopy for Non-Destructive Measurement and Genetic Analysis of Amounts and Types of Epicuticular Waxes on Onion Leaves Molecules doi: 10.3390/molecules25153454 Authors: Eduardo D. Munaiz Philip A. Townsend Michael J. Havey Epicuticular waxes on the surface of plant leaves are important for the tolerance to abiotic stresses and plant–parasite interactions. In the onion (Allium cepa L.), the variation for the amounts and...
Molecules, Vol. 25, Pages 3453: Anti-Apoptotic Effects of Carotenoids in Neurodegeneration Molecules doi: 10.3390/molecules25153453 Authors: Han-A Park Mary Margaret Hayden Sydni Bannerman Joseph Jansen Kristi M. Crowe-White Apoptosis, programmed cell death type I, is a critical part of neurodegeneration in cerebral ischemia, Parkinson’s, and Alzheimer’s disease. Apoptosis begins with activation of pro-death proteins Bax and Bak, release of cytochrome...
Molecules, Vol. 25, Pages 3451: Mosquitocidal and Anti-Inflammatory Properties of The Essential Oils Obtained from Monoecious, Male, and Female Inflorescences of Hemp (Cannabis sativa L.) and Their Encapsulation in Nanoemulsions Molecules doi: 10.3390/molecules25153451 Authors: Paolo Rossi Alessia Cappelli Oliviero Marinelli Matteo Valzano Lucia Pavoni Giulia Bonacucina Riccardo Petrelli Pierluigi Pompei Eugenia Mazzara Irene Ricci Filippo Maggi Massimo Nabissi...
Molecules, Vol. 25, Pages 3450: Corroles and Hexaphyrins: Synthesis and Application in Cancer Photodynamic Therapy Molecules doi: 10.3390/molecules25153450 Authors: Susana M. M. Lopes Marta Pineiro Teresa M. V. D. Pinho e Melo Corroles and hexaphyrins are porphyrinoids with great potential for diverse applications. Like porphyrins, many of their applications are based on their unique capability to interact with light, i.e., based on their photophysical properties. Corroles have...
Molecules, Vol. 25, Pages 3452: Advances in Saponin Diversity of Panax ginseng Molecules doi: 10.3390/molecules25153452 Authors: Xiangmin Piao Hao Zhang Jong Pyo Kang Dong Uk Yang Yali Li Shifeng Pang Yinping Jin Deok Chun Yang Yingping Wang Ginsenosides are the major bioactive constituents of Panax ginseng, which have pharmacological effects. Although there are several reviews in regards to ginsenosides, new ginsenosides have been detected continually in recent...
Molecules, Vol. 25, Pages 3449: Design of Targeted Nanostructured Coordination Polymers (NCPs) for Cancer Therapy Molecules doi: 10.3390/molecules25153449 Authors: Fernando Novio Conventional cancer chemotherapy presents notable drug side effects due to non-selective action of the chemotherapeutics to normal cells. Nanoparticles decorated with receptor-specific ligands on the surface have shown an important role in improving site-selective binding, retention, and drug delivery to the...
Molecules, Vol. 25, Pages 3448: Systematic Evaluation of Different Coating Chemistries Used in Thin-Film Microextraction Molecules doi: 10.3390/molecules25153448 Authors: Jia-Wei Liu Khaled Murtada Nathaly Reyes-Garcés Janusz Pawliszyn A systematic evaluation of eight different coatings made of solid phase extraction (SPE) and carbon-based sorbents immobilized with polyacrylonitrile in the thin-film microextraction (TFME) format using LC-MS/MS was described. The investigated...
Molecules, Vol. 25, Pages 3446: VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder Molecules doi: 10.3390/molecules25153446 Authors: Soumitra Samanta Steve O’Hagan Neil Swainston Timothy J. Roberts Douglas B. Kell Molecular similarity is an elusive but core “unsupervised” cheminformatics concept, yet different “fingerprint” encodings of molecular structures return very different similarity values, even...
Molecules, Vol. 25, Pages 3445: Tuning Surface Morphology of Fluorescent Hydrogels Using a Vortex Fluidic Device Molecules doi: 10.3390/molecules25153445 Authors: Javad Tavakoli Colin L. Raston Youhong Tang In recent decades, microfluidic techniques have been extensively used to advance hydrogel design and control the architectural features on the micro- and nanoscale. The major challenges with the microfluidic approach are clogging and limited architectural features: notably,...
Molecules, Vol. 25, Pages 3442: 3D Bioprinted Osteogenic Tissue Models for In Vitro Drug Screening Molecules doi: 10.3390/molecules25153442 Authors: Erick Breathwaite Jessica Weaver Justin Odanga Myra dela Pena-Ponce Jung Bok Lee Metabolic bone disease affects hundreds of millions of people worldwide, and as a result, in vitro models of bone tissue have become essential tools to help analyze bone pathogenesis, develop drug screening, and test potential therapeutic strategies....
Molecules, Vol. 25, Pages 3447: More Efficient Prussian Blue Nanoparticles for an Improved Caesium Decontamination from Aqueous Solutions and Biological Fluids Molecules doi: 10.3390/molecules25153447 Authors: Fabio Carniato Giorgio Gatti Chiara Vittoni Andrey M. Katsev Matteo Guidotti Claudio Evangelisti Chiara Bisio Any release of radioactive cesium-137, due to unintentional accidents in nuclear plants, represents a dangerous threat for human health and the environment....
Molecules, Vol. 25, Pages 3443: Bioactive Peptides and Dietary Polyphenols: Two Sides of the Same Coin Molecules doi: 10.3390/molecules25153443 Authors: Rosa Pérez-Gregorio Susana Soares Nuno Mateus Victor de Freitas The call for health-promoting nutraceuticals and functional foods containing bioactive compounds is growing. Among the great diversity of functional phytochemicals, polyphenols and, more recently, bioactive peptides have stood out as functional compounds. The amount...
Molecules, Vol. 25, Pages 3440: Moonlighting Proteins in the Fuzzy Logic of Cellular Metabolism Molecules doi: 10.3390/molecules25153440 Authors: Haipeng Liu Constance J. Jeffery The numerous interconnected biochemical pathways that make up the metabolism of a living cell comprise a fuzzy logic system because of its high level of complexity and our inability to fully understand, predict, and model the many activities, how they interact, and their regulation. Each cell contains thousands...
Molecules, Vol. 25, Pages 3441: Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis Molecules doi: 10.3390/molecules25153441 Authors: Raffaella Colombo Adele Papetti Mycotoxins are considered one of the most dangerous agricultural and food contaminants. They are toxic and the development of rapid and sensitive analytical methods to detect and quantify them is a very important issue in the context of food safety and animal/human health. The need...
Molecules, Vol. 25, Pages 3444: Photoinduced Polymerization of Eugenol-Derived Methacrylates Molecules doi: 10.3390/molecules25153444 Authors: Samantha Molina-Gutiérrez Sara Dalle Vacche Alessandra Vitale Vincent Ladmiral Sylvain Caillol Roberta Bongiovanni Patrick Lacroix-Desmazes Biobased monomers have been used to replace their petroleum counterparts in the synthesis of polymers that are aimed at different applications. However, environmentally friendly polymerization...
Molecules, Vol. 25, Pages 3439: Synthesis and Antimicrobial Evaluation of Some New Organic Tellurium Compounds Based on Pyrazole Derivatives Molecules doi: 10.3390/molecules25153439 Authors: Asmaa B. Sabti Adil A. Al-Fregi Majeed Y. Yousif A novel series of organic tellurium compounds based on pyrazole derivatives with a general formula of ArTeBr3 and Ar2TeBr2 [Ar = 2-(3-(4-substituted phenyl)-5-(2-chlorophenyl)-1H-pyrazol-1-yl)-3,5-dinitrophenyl] were obtained by the refluxing...
Molecules, Vol. 25, Pages 3438: Chemistry of Fluorinated Pyrimidines in the Era of Personalized Medicine Molecules doi: 10.3390/molecules25153438 Authors: William H. Gmeiner We review developments in fluorine chemistry contributing to the more precise use of fluorinated pyrimidines (FPs) to treat cancer. 5-Fluorouracil (5-FU) is the most widely used FP and is used to treat > 2 million cancer patients each year. We review methods for 5-FU synthesis, including the incorporation...
Molecules, Vol. 25, Pages 3437: Anti-VCAM-1 and Anti-IL4Rα Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy Molecules doi: 10.3390/molecules25153437 Authors: Raja Chinnappan Achraf Al Faraj Anas M. Abdel Rahman Khalid M. Abu-Salah Fouzi Mouffouk Mohammed Zourob The surface protein overexpressed on cancer cells can be used as biomarkers for early detection of specific diseases. Anti-VCAM-1 and anti-IL4Rα...
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