Introduction: The WHO declared 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) a public health emergency of international concern. The National and Regional Health System has been reorganized, and many oncological patients died during this period or had to interrupt their therapies. This study summarizes a single-centre experience, during the COVID-19 period in Italy, in the treatment of brain metastases with Gamma Knife stereotactic radiosurgery (GKRS). Methods: We retrospectively...
Stereotact Funct Neurosurg
Stereotact Funct Neurosurg
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An electron micrograph showing glycogen granules forming highly ordered, honeycomb structures in the subsarcolemmal area of muscle fibers, in a patient with glycogen storage disease due to a mutation in the PYGM gene, which codes for myophosphorylase, the enzyme catalyzing the initial step of glycogen breakdown. See Echaniz‐Laguna et al., pp. 274–282, in this issue.
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Abstract In this opinion essay, I address the perennial binding problem, that is to say of how independently processed visual attributes such as form, colour and motion are brought together to give us a unified and holistic picture of the visual world. A solution to this central issue in neurobiology remains as elusive as ever. No one knows today how it is implemented. The issue is not a new one and, though discussed most commonly in the context of the visual brain, it is not unique to it either....
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Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disorder with cardinal manifestation of cognitive dysfunction. The limitation to avail a successful drug candidate encourages researchers to establish an appropriate animal model in the novel anti-AD drug discovery process. In this context, the mechanism of mitochondrial dysfunction in cognitive deficit animals is yet to be established for intracerebroventricular injection of streptozotocin (ICV-STZ). Experimental...
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