Antibiotics, Vol. 9, Pages 460: The pathogen Mycoplasma dispar Shows High Minimum Inhibitory Concentrations for Antimicrobials Commonly Used for Bovine Respiratory Disease Antibiotics doi: 10.3390/antibiotics9080460 Authors: Bottinelli Merenda Gastaldelli Picchi Stefani Nicholas Catania Mycoplasma dispar is an overlooked pathogen often involved in bovine respiratory disease (BRD), which affects cattle around the world. BRD results in lost production and high...
Antibiotics, Vol. 9, Pages 461: Bismuth Nanoantibiotics Display Anticandidal Activity and Disrupt the Biofilm and Cell Morphology of the Emergent Pathogenic Yeast Candida auris Antibiotics doi: 10.3390/antibiotics9080461 Authors: Vazquez-Munoz Lopez Lopez-Ribot Candida auris is an emergent multidrug-resistant pathogenic yeast, which forms biofilms resistant to antifungals, sanitizing procedures, and harsh environmental conditions. Antimicrobial nanomaterials represent an alternative...
Antibiotics, Vol. 9, Pages 458: Post-Antibiotic Effect of Ampicillin and Levofloxacin to Escherichia coli and Staphylococcus aureus Based on Microscopic Imaging Analysis Antibiotics doi: 10.3390/antibiotics9080458 Authors: Farjana Hanif Proma Mohiuddin Khan Shourav Jungil Choi Post-antibiotic effect (PAE) is the continued suppression of bacterial growth following a limited exposure to an antimicrobial agent. The presence of PAE needs consequential consideration in designing antibiotic...
Antibiotics, Vol. 9, Pages 457: Antimicrobial Property and Mode of Action of the Skin Peptides of the Sado Wrinkled Frog, Glandirana susurra, against Animal and Plant Pathogens Antibiotics doi: 10.3390/antibiotics9080457 Authors: Daisuke Ogawa Manami Suzuki Yuriko Inamura Kaito Saito Itaru Hasunuma Tetsuya Kobayashi Sakae Kikuyama Shawichi Iwamuro The Sado wrinkled frog Glandirana susurra has recently been classified as a new frog species endemic to Sado Island,...
Antibiotics, Vol. 9, Pages 459: HPLC-DAD and UHPLC/QTOF-MS Analysis of Polyphenols in Extracts of the African Species Combretum padoides, C. zeyheri and C. psidioides Related to Their Antimycobacterial Activity Antibiotics doi: 10.3390/antibiotics9080459 Authors: Pia Fyhrquist Enass Y. A. Salih Satu Helenius Into Laakso Riitta Julkunen-Tiitto Combretum padoides Engl. & Diels, C. psidioides Welv. and C. zeyheri Sond. are used forthe treatment of infections and tuberculosis...
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Antibodies, Vol. 9, Pages 36: Characterization of Co-Formulated High-Concentration Broadly Neutralizing Anti-HIV-1 Monoclonal Antibodies for Subcutaneous Administration Antibodies doi: 10.3390/antib9030036 Authors: Vaneet K. Sharma Bijay Misra Kevin T. McManus Sreenivas Avula Kaliappanadar Nellaiappan Marina Caskey Jill Horowitz Michel C. Nussenzweig Michael S. Seaman Indu Javeri Antu K. Dey The discovery of numerous potent and broad neutralizing antibodies...
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Antioxidants, Vol. 9, Pages 683: Sex Difference Impacts on the Relationship between Paraoxonase-1 (PON1) and Type 2 Diabetes Antioxidants doi: 10.3390/antiox9080683 Authors: Rosta Trentini Passaro Zuliani Sanz Bosi Bonaccorsi Bellini Cervellati Type-2 diabetes (T2D) and its cardiovascular complications are related to sex. Increasing evidence suggests that paraoxonase 1 (PON1) activity, an antioxidant enzyme bound to high-density lipoproteins (HDL), is...
Antioxidants, Vol. 9, Pages 680: Comparative Study of Protective Action of Exogenous 2-Cys Peroxiredoxins (Prx1 and Prx2) Under Renal Ischemia-Reperfusion Injury Antioxidants doi: 10.3390/antiox9080680 Authors: Sharapov Goncharov Filkov Trofimenko Boyarintsev Novoselov The pathogenesis of ischemia-reperfusion (I/R) injuries is based on oxidative stress caused by a sharp increase in the concentration of free radicals, reactive oxygen species (ROS) and secondary products...
Antioxidants, Vol. 9, Pages 681: Reactive Oxygen Species and Antioxidant Defense in Plants under Abiotic Stress: Revisiting the Crucial Role of a Universal Defense Regulator Antioxidants doi: 10.3390/antiox9080681 Authors: Mirza Hasanuzzaman M.H.M. Borhannuddin Bhuyan Faisal Zulfiqar Ali Raza Sayed Mohammad Mohsin Jubayer Al Mahmud Masayuki Fujita Vasileios Fotopoulos Global climate change and associated adverse abiotic stress conditions, such as drought, salinity,...
Antioxidants, Vol. 9, Pages 682: Saponin Formosanin C-induced Ferritinophagy and Ferroptosis in Human Hepatocellular Carcinoma Cellsa Antioxidants doi: 10.3390/antiox9080682 Authors: Lin Tang Wu Shaw Su Ferroptosis, a recently discovered form of iron-dependent cell death, requires an increased level of lipid-reactive oxygen species (ROS). Ferritinophagy, a ferritin degradation pathway, depends on a selective autophagic cargo receptor (NCOA4). By screening various types...
Antioxidants, Vol. 9, Pages 678: Effects of Microwave-Assisted Extraction Conditions on Antioxidant Capacity of Sweet Tea (Lithocarpus polystachyus Rehd.) Antioxidants doi: 10.3390/antiox9080678 Authors: Ao Shang Min Luo Ren-You Gan Xiao-Yu Xu Yu Xia Huan Guo Yi Liu Hua-Bin Li In this study, the effects of microwave-assisted extraction conditions on antioxidant capacity of sweet tea (Lithocarpus polystachyus Rehd.) were studied and the antioxidants in the extract...
Antioxidants, Vol. 9, Pages 679: Diabetes Upregulates Oxidative Stress and Downregulates Cardiac Protection to Exacerbate Myocardial Ischemia/Reperfusion Injury in Rats Antioxidants doi: 10.3390/antiox9080679 Authors: Chen-Yen Chien Ting-Jui Wen Yu-Hsiuan Cheng Yi-Ting Tsai Chih-Yao Chiang Chiang-Ting Chien Diabetes exacerbates myocardial ischemia/reperfusion (IR) injury by incompletely understood mechanisms. We explored whether diabetes diminished BAG3/Bcl-2/Nrf-2/HO-1-mediated...
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Atmosphere, Vol. 11, Pages 802: Airborne Bacterial and Eukaryotic Community Structure across the United Kingdom Revealed by High-Throughput Sequencing Atmosphere doi: 10.3390/atmos11080802 Authors: Hokyung Song Ian Crawford Jonathan R. Lloyd Clare H. Robinson Christopher Boothman Keith Bower Martin Gallagher Grant Allen David Topping Primary biological aerosols often include allergenic and pathogenic microorganisms posing potential risks to human health. Moreover,...
Atmosphere, Vol. 11, Pages 801: The Impact of Stochastic Physics-Based Hybrid GSI/EnKF Data Assimilation on Hurricane Forecasts Using EMC Operational Hurricane Modeling System Atmosphere doi: 10.3390/atmos11080801 Authors: Zhang Tong Sippel Mehra Zhang Wu Liu Dong Ma Winterbottom Wang Zhu Liu Kim Thomas Sheinin Bi Tallapragada The National Oceanic and Atmospheric Administration’s (NOAA) cloud-permitting high-resolution...
Atmosphere, Vol. 11, Pages 800: Microclimate in Rooms Equipped with Decentralized Façade Ventilation Device Atmosphere doi: 10.3390/atmos11080800 Authors: Zender-Świercz Many building are characterized by insufficient air exchange, which may result in the symptoms of sick building syndrome (SBS). A large number of existing buildings are equipped with natural ventilation, whose work is disturbed by activities going to energy-saving. The thermomodernization activities are about mounting...
Atmosphere, Vol. 11, Pages 799: Short-Term Responses of Air Quality to Changes in Emissions under the Representative Concentration Pathway 4.5 Scenario over Brazil Atmosphere doi: 10.3390/atmos11080799 Authors: Daniel Schuch Maria de Fatima Andrade Yang Zhang Edmilson Dias de Freitas Michelle L. Bell Brazil, one of the world’s fastest-growing economies, is the fifth most populous country and is experiencing accelerated urbanization. This combination of factors causes...
Atmosphere, Vol. 11, Pages 798: Tree Surface Temperature in a Primary Tropical Rain Forest Atmosphere doi: 10.3390/atmos11080798 Authors: Qinghai Song Chenna Sun Yun Deng He Bai Yiping Zhang Hui Yu Jing Zhang Liqing Sha Wenjun Zhou Yuntong Liu As one of the important factors affecting plant productivity and plant distribution, temperature also affects the physiological and ecological characteristics of plants to a large extent. We report canopy leaf temperature...
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Behavioral Sciences, Vol. 10, Pages 123: Better to Be Alone than in Bad Company: Cognate Synonyms Impair Word Learning Behavioral Sciences doi: 10.3390/bs10080123 Authors: Eneko Antón Jon Andoni Duñabeitia The effects of cognate synonymy in L2 word learning are explored. Participants learned the names of well-known concrete concepts in a new fictional language following a picture-word association paradigm. Half of the concepts (set A) had two possible translations in the new language...
Behavioral Sciences, Vol. 10, Pages 122: Details of the Contents of Paranoid Thoughts in Help-Seeking Adolescents with Psychotic-Like Experiences and Continuity with Bullying and Victimization: A Pilot Study Behavioral Sciences doi: 10.3390/bs10080122 Authors: Gennaro Catone Antonella Gritti Katia Russo Pia Santangelo Raffaella Iuliano Carmela Bravaccio Simone Pisano Background: Psychosis recognizes an interaction between biological and social environmental factors....
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Bioengineering, Vol. 7, Pages 81: Dynamic Properties of Heart Fragments from Different Regions and Their Synchronization Bioengineering doi: 10.3390/bioengineering7030081 Authors: Shin Arai Kento Lloyd Tomonori Takahashi Kazuki Mammoto Takashi Miyazawa Kei Tamura Tomoyuki Kaneko Kentaro Ishida Yuuta Moriyama Toshiyuki Mitsui The dynamic properties of the heart differ based on the regions that effectively circulate blood throughout the body with each heartbeat....
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Biology, Vol. 9, Pages 194: Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes, and Experimental Models Biology doi: 10.3390/biology9080194 Authors: Yuchen He Zhong Li Peter G. Alexander Brian D. Ocasio-Nieves Lauren Yocum Hang Lin Rocky S. Tuan As the most common chronic degenerative joint disease, osteoarthritis (OA) is the leading cause of pain and physical disability, affecting millions of people worldwide. Mainly characterized by...
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Biomedicines, Vol. 8, Pages 252: Novel Nargenicin A1 Analog Inhibits Angiogenesis by Downregulating the Endothelial VEGF/VEGFR2 Signaling and Tumoral HIF-1α/VEGF Pathway Biomedicines doi: 10.3390/biomedicines8080252 Authors: Jang Mi Han Ye Seul Choi Dipesh Dhakal Jae Kyung Sohng Hye Jin Jung Targeting angiogenesis is an attractive strategy for the treatment of angiogenesis-related diseases, including cancer. We previously identified 23-demethyl 8,13-deoxynargenicin (compound...
Biomedicines, Vol. 8, Pages 251: Astemizole Sensitizes Adrenocortical Carcinoma Cells to Doxorubicin by Inhibiting Patched Drug Efflux Activity Biomedicines doi: 10.3390/biomedicines8080251 Authors: Anida Hasanovic Méliné Simsir Frank S. Choveau Enzo Lalli Isabelle Mus-Veteau Adrenocortical carcinoma (ACC) presents a high risk of relapse and metastases with outcomes not improving despite extensive research and new targeted therapies. We recently showed that the Hedgehog receptor...
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Biomolecules, Vol. 10, Pages 1124: Attachable Hydrogel Containing Indocyanine Green for Selective Photothermal Therapy against Melanoma Biomolecules doi: 10.3390/biom10081124 Authors: Hwang Jin Melanoma is the most lethal form of skin cancer because it spreads easily to other tissues, thereby decreasing the efficiency of its treatment via chemo-, radio-, and surgical therapies. We suggest the application of an attachable hydrogel for the treatment of melanoma whereby the size and...
Biomolecules, Vol. 10, Pages 1123: The Development of a Skin Cancer Classification System for Pigmented Skin Lesions Using Deep Learning Biomolecules doi: 10.3390/biom10081123 Authors: Shunichi Jinnai Naoya Yamazaki Yuichiro Hirano Yohei Sugawara Yuichiro Ohe Ryuji Hamamoto Recent studies have demonstrated the usefulness of convolutional neural networks (CNNs) to classify images of melanoma, with accuracies comparable to those achieved by dermatologists. However, the performance...
Biomolecules, Vol. 10, Pages 1122: Regulation of Protein Post-Translational Modifications on Metabolism of Actinomycetes Biomolecules doi: 10.3390/biom10081122 Authors: Chen-Fan Sun Yong-Quan Li Xu-Ming Mao Protein post-translational modification (PTM) is a reversible process, which can dynamically regulate the metabolic state of cells through regulation of protein structure, activity, localization or protein–protein interactions. Actinomycetes are present in the soil,...
Biomolecules, Vol. 10, Pages 1121: Glycine in Water Favors the Polyproline II State Biomolecules doi: 10.3390/biom10081121 Authors: Brian Andrews Shuting Zhang Reinhard Schweitzer-Stenner Brigita Urbanc Conformational preferences of amino acid residues in water are determined by the backbone and side-chain properties. Alanine is known for its high polyproline II (pPII) propensity. The question of relative contributions of the backbone and side chain to the conformational preferences...
Biomolecules, Vol. 10, Pages 1120: Aberrant Membrane Composition and Biophysical Properties Impair Erythrocyte Morphology and Functionality in Elliptocytosis Biomolecules doi: 10.3390/biom10081120 Authors: Hélène Pollet Anne-Sophie Cloos Amaury Stommen Juliette Vanderroost Louise Conrard Adrien Paquot Marine Ghodsi Mélanie Carquin Catherine Léonard Manuel Guthmann Maxime Lingurski Christiane Vermylen Theodore Killian Laurent Gatto Mark Rider Sébastien...
Biomolecules, Vol. 10, Pages 1119: Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction Biomolecules doi: 10.3390/biom10081119 Authors: Amany Tawfik Yara A. Samra Nehal M. Elsherbiny Mohamed Al-Shabrawey Elevated plasma homocysteine (Hcy) level, known as hyperhomocysteinemia (HHcy) has been linked to different systemic and neurological diseases, well-known as a risk factor for systemic atherosclerosis and cardiovascular disease (CVD) and has been identified...
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Biosensors, Vol. 10, Pages 86: Development of a Ratiometric Fluorescent Glucose Sensor Using an Oxygen-Sensing Membrane Immobilized with Glucose Oxidase for the Detection of Glucose in Tears Biosensors doi: 10.3390/bios10080086 Authors: Hong Dinh Duong Ok-Jae Sohn Jong Il Rhee Glucose concentration is an important parameter in biomedicine since glucose is involved in many metabolic pathways in organisms. Many methods for glucose detection have been developed for use in various...
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Brain Sciences, Vol. 10, Pages 496: Alexithymia Profile in Relation to Negative Affect in Parents of Autistic and Typically Developing Young Children Brain Sciences doi: 10.3390/brainsci10080496 Authors: Elisa Leonardi Antonio Cerasa Francesca Isabella Famà Cristina Carrozza Letteria Spadaro Renato Scifo Sabrina Baieli Flavia Marino Gennaro Tartarisco David Vagni Giovanni Pioggia Liliana Ruta In our study, we explored the construct of alexithymia in parents...
Brain Sciences, Vol. 10, Pages 495: Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms Brain Sciences doi: 10.3390/brainsci10080495 Authors: Petr Vachata Jan Lodin Aleš Hejčl Filip Cihlář Martin Sameš Cerebral vasospasm and subsequent delayed ischemic neurological deficit is a typical sequela of acute subarachnoid hemorrhage after aneurysm rupture. The occurrence of vasospasms after uncomplicated surgery of an unruptured...
Brain Sciences, Vol. 10, Pages 497: Enhancing Memory for Relationship Actions by Transcranial Direct Current Stimulation of the Superior Temporal Sulcus Brain Sciences doi: 10.3390/brainsci10080497 Authors: Hipólito Marrero Sara Nila Yagual Enrique García-Marco Elena Gámez David Beltrán Jose Miguel Díaz Mabel Urrutia We examine the effect of transcranial direct current stimulation (tDCS) of right superior temporal sulcus (rSTS) in memorization of approach/avoidance...
Brain Sciences, Vol. 10, Pages 494: On Your Mark, Get Set, Self-Control, Go: A Differentiated View on the Cortical Hemodynamics of Self-Control during Sprint Start Brain Sciences doi: 10.3390/brainsci10080494 Authors: Kim-Marie Stadler Wanja Wolff Julia Schüler Most sports are self-control demanding. For example, during a sprint start, athletes have to respond as fast as possible to the start signal (action initiation) while suppressing the urge to start too early (action inhibition)....
Brain Sciences, Vol. 10, Pages 493: Carbohydrate Mouth Rinse Mitigates Mental Fatigue Effects on Maximal Incremental Test Performance, but Not in Cortical Alterations Brain Sciences doi: 10.3390/brainsci10080493 Authors: Cayque Brietzke Paulo Estevão Franco-Alvarenga Raul Canestri Márcio Fagundes Goethel Ítalo Vínicius Vitor de Salles Painelli Tony Meireles Santos Florentina Johanna Hettinga Flávio Oliveira Pires Detrimental mental fatigue effects on exercise...
Brain Sciences, Vol. 10, Pages 492: Rehabilitation of Adult Patients with Primary Brain Tumors: A Narrative Review Brain Sciences doi: 10.3390/brainsci10080492 Authors: Parth Thakkar Brian D. Greenwald Palak Patel Rehabilitative measures have been shown to benefit patients with primary brain tumors (PBT). To provide a high quality of care, clinicians should be aware of common challenges in this population including a variety of medical complications, symptoms, and impairments,...
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Cancers, Vol. 12, Pages 2110: Circulating Exosomes Inhibit B Cell Proliferation and Activity Cancers doi: 10.3390/cancers12082110 Authors: Jan C. Schroeder Lisa Puntigam Linda Hofmann Sandra S. Jeske Inga J. Beccard Johannes Doescher Simon Laban Thomas K. Hoffmann Cornelia Brunner Marie-Nicole Theodoraki Patrick J. Schuler (1) Background: Head and neck squamous cell carcinoma (HNSCC) is characterized by a distinctive suppression of the anti-tumor immunity,...
Cancers, Vol. 12, Pages 2112: Epithelioid Sarcoma—From Genetics to Clinical Practice Cancers doi: 10.3390/cancers12082112 Authors: Anna M. Czarnecka Pawel Sobczuk Michal Kostrzanowski Mateusz Spalek Marzanna Chojnacka Anna Szumera-Cieckiewicz Piotr Rutkowski Epithelioid sarcoma is a mesenchymal soft tissue sarcoma often arising in the extremities, usually in young adults with a pick of incidence at 35 years of age. Epithelioid sarcoma (ES) is characterized...
Cancers, Vol. 12, Pages 2111: MicroRNA-21-Enriched Exosomes as Epigenetic Regulators in Melanomagenesis and Melanoma Progression: The Impact of Western Lifestyle Factors Cancers doi: 10.3390/cancers12082111 Authors: Bodo C. Melnik Swen Malte John Pedro Carrera-Bastos Gerd Schmitz DNA mutation-induced activation of RAS-BRAF-MEK-ERK signaling associated with intermittent or chronic ultraviolet (UV) irradiation cannot exclusively explain the excessive increase of malignant melanoma...
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